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Table 1 Details of the included studies

From: Work-related outcomes in randomised placebo-controlled pain trials: a systematic review and meta-analysis

Data sets

Articles

Conditions

Active interventions

Patients

Work-related outcomes

Study duration (in weeks)

OQS score

1

Albert et al. 2013 [10]

Chr. back pain

Amoxicillin–Clavulanate

162

Time lost from work

52

5

2

Baron et al. 2010 [14]

Chr. back pain

Pregabalin

217

WPAI

5

4

3

Carlsson & Sjölund 2001 [19]

Chr. back pain

Acupuncture, electroacupuncture

51

Employment status

32

5

4

Jarzem et al. 2005 [25]

Chr. back pain

TENS

350

McGill Work Scale

12

5

5

Lehmann et al. 1986 [29]

Chr. back pain

TENS, electroacupuncture

54

Employment status

3

4

6

Licciardone et al. 2003 [30]

Chr. back pain

Osteopathic manipulative treatment

91

Time lost from work

20

3

7

Skljarevski et al. 2009 [34]

Chr. back pain

Duloxetine

404

BPI-I

13

5

8

Skljarevski et al. 2010a [35]

Chr. back pain

Duloxetine

236

BPI-I, WPAI

13

4

9

Skljarevski et al. 2010b [36]

Chr. back pain

Duloxetine

401

BPI-I, WPAI

12

3

10

He et al. 2005 [24]

Chr. neck pain

Body acupuncture + body electrostimulation + ear acupressure

24

Activity impairment at work

4

2

11

Manchikanti et al. 2010 [31]

Chr. neck pain

Bupivacaine and steroid injection

120

Employability, employment status

96

5

12

Bennett et al. 2003 + 2005 [16, 17]

Fibromyalgia

Tramadol-Acetaminophen

315

FIQ, time lost from work, SF-36

8

3

13

Bradley et al. 2010 [18] + Arnold et al. 2009 [12] (Arnold et al. 2005 [11] + Chappell et al. 2008 [20])

Fibromyalgia

Duloxetine

1332

Bradley 2010 [18]: FIQ, Arnold 2009 [12]: SDS (Arnold 2005 [11]: BPI, Chappell 2008 [20]: SDS)

12-28

Review (Arnold et al. 2005 [11]: 5, Chappell et al. 2008 [20]: 3)

14

Straube et al. 2011 [4]

Fibromyalgia

Pregabalin

2757

FIQ, time lost from work, SF-36, SDS, MAF

8-14

Review

15

Chappell et al. 2009 [21]

Osteoarthritis (knee)

Duloxetine

231

BPI-I

13

5

16

Chappell et al. 2011 [22]

Osteoarthritis (knee)

Duloxetine

256

BPI-I

13

5

17

Markenson et al. 2005 [32]

Osteoarthritis

Oxycodone

109

BPI-I

12

4

18

Kavanaugh et al. 2006 [26]

Psoriatic arthritis

Infliximab

200

SF-36, employment status, employability, impact on productivity at work (VAS), time lost from work

22

3

19

Kavanaugh et al. 2013 [28]

Psoriatic arthritis

Golimumab

405

Impact on productivity at work (VAS)

24

4

20

Egsmose et al. 1997 [23]

Reactive arthritis

Sulphasalazine

83

Time lost from work

24

3

21

Bejarano et al. 2008 [15]

Rheumatoid arthritis

Adalimumab + MTX

148

Employment status, WIS, Time lost from work

56

5

22

Kavanaugh et al. 2009 [27]

Rheumatoid arthritis

Certolizumab pegol + MTX

1601

WPS, time lost from work

24 + 52

3

23

Meireles et al. 2010 [33]

Rheumatoid arthritis

Low-level laser therapy

82

DASH

8

5

24

Smolen et al. 2006 [37]

Rheumatoid arthritis

Infliximab + MTX

1004

Employability, time lost from work

54

5

25

Strand et al. 1999 [38]

Rheumatoid arthritis

Leflunomide, MTX

482

Productivity at work

48

4

26

Barkham et al. 2010 [13]

Ankylosing spondylitis

Entanercept

40

WIS, time lost from work

12

3

27

van der Heijde et al. 2006 [39]

Ankylosing spondylitis

Infliximab

279

SF-36, impact on productivity at work (VAS), time lost from work

24

4

  1. BPI-I – Brief Pain Inventory: Interference with normal work; chr. – chronic; DASH – Disabilities of the Arm, Shoulder and Hand Questionnaire; FIQ – Fibromyalgia Impact Questionnaire; MAF – Multidimensional Assessment of Fatigue; MTX – methotrexate; OQS – Oxford Quality Scale; SDS – Sheehan Disability Scale; SF-36 – Short Form 36 Health Survey; TENS – transcutaneous electrical nerve stimulation; VAS – visual analogue scale; WIS – Work Instability Scale; WPAI – Work Productivity and Activity Impairment Questionnaire; WPS – Work Productivity Survey. For reviews, information in brackets refers to the primary publications on which the reviews were based.