Fig. 6

Vit C protected against Cr (VI)-induced hepatotoxicity in vivo. All rats were given the drugs by gavage at a dose of 0.5 ml/100 g body weight daily for a week (seven consecutive days). Groups are indicated by pretreatment + treatment as follows: Con, Vit C, Cr (VI) (8.84 mg/kg.bw), Vit C+ Cr (VI) (8.84 mg/kg.bw), Cr (VI) (17.68 mg/kg.bw), and Vit C+ Cr (VI) (17.68 mg/kg.bw). a Effect of Vit C pretreatment on Cr (VI)-induced alterations in rat liver histology. b The chromium contents in stool, urine, liver and plasma. c AST and ALT activities. d GSH, SOD, and MDA levels. e Free radical scavenging capacity. Data represent mean ± SD. *p < 0.05, compared with control group. ^# p < 0.05, compared with the Cr (VI) alone treatment group