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Table 3 Correlations between blood lead level and electrophysiological parameters, motor evoked potentials and indices of nerve excitability test

From: Nerve excitability test and lead toxicity: a case-control study

 

Parameters

Controls (± SD)

Workers (± SD)

p value

NCS

Distal latency (ms)

3.06 (± 0.27)

3.69 (± 0.64)

0.002

Distal CMAP amplitude (mV)

7.55 (± 0.65)

6.63 (± 1.97)

0.108

MNCV (m/s)

58.14 (± 6.35)

55.66 (± 2.72)

0.037

Proximal latency (ms)#1

10.44 (± 0.53)

10.76 (± 1.15)

0.446

MEP

Latency (ms)

17.44 (± 9.73)

23.47 (± 1.80)

0.000

NET

Stimulus-Response curve

 

Stim. 50% max resp. (mA)

3.66 (± 2.52)

4.96 (± 1.08)

0.001

SR slope

7.45 (± 5.47)

5.13 (± 1.61)

0.003

Peak response (mV)

2.03 (± 1.05)

2.93 (± 0.91)

0.014

Threshold electrotonus

 

S1 (TEh 20–40 ms)

-90.63 (± 48.03)

-96.29 (± 8.38)

0.046

S3 (TEh 90–100 ms)

-119.22 (± 64.85)

-132.59 (± 18.30)

0.027

  1. #1 The conduction time from spinal cord to the stimulation site
  2. SD: standard deviation; BLL: blood lead level; NCS: nerve conduction study; MEP: motor evoked potential; NET: nerve excitability test; CMAP: compound muscle action potential; MNCV: motor nerve conduction velocity; SR slope: stimulus-response slope; TEh: hyperpolarization condition of threshold electrotonus; r: correlation coefficient; Stim. 50% max resp.: stimulus for 50% of max response