Figure 7
Proliferative activity of glandular and surface epithelial cells. To assess the proliferative activity, an in vivo BrdU-assay and AgNOR-analysis were performed. Positive staining indicating BrdU incorporation was only found occasionally in the surface epithelium and in glands (A, B). In contrast, AgNOR-analysis demonstrated argyrophilic nucleolar organizer regions (C, D) and the AgNOR index (E) revealed significant differences (*, p < 0.05) between exposed and nonexposed groups. Original magnification ×400 (×1000, D).