Persistently elevated T cell interferon-γ responses after treatment for latent tuberculosis infection among health care workers in India: a preliminary report

Table 1 T cell interferon-γ responses in nursing students treated for latent tuberculosis infection with isoniazid preventive therapy for 6 months (N = 10)

ID number	Age at baseline	Sex M/F	BCG scar (Y/N)	TST at baseline (mm)	IFN-γ responses at baseline (Jan/Feb 2004)		IFN-γ responses at second survey, 4 months after INH treatment (Jan 2005)		IFN-γ responses at third survey, 10 months after INH treatment (July 2005)
					Result (Pos/Neg)*	IU/mL**	Result (Pos/Neg)*	IU/mL**	Result (Pos/Neg)*	IU/mL**
10055	19	F	Y	14	P	10.0	P	10.0	P	10.0
10066	19	F	Y	15	P	10.0	P	2.55	P	10.0
10069	19	F	Y	17	P	9.55	P	10.0	P	10.0
10077	19	F	N	19	P	10.0	P	4.34	P	2.04
10082	19	F	Y	18	P	10.0	P	10.0	P	5.86
10089	19	F	Y	16	P	10.0	P	8.35	P	1.51
10093	19	F	N	20	P	10.0	P	5.13	P	3.31
10115	24	F	Y	17	P	0.39	N	0	N	0.21
10282	19	F	N	15	P	1.21	P	4.40	P	10.0
10290	18	F	N	18	P	10.0	P	4.81	P	10.0
Mean (SD)						8.1 (3.9)		5.9 (3.5)		6.3 (4.2)
Median						10.0		5.0		7.9

*QFT-G cut-point for positivity: ≥0.35 IU/mL
** IFN-γ values >10.0 IU/mL have been shown as 10 IU/mL
TST: tuberculin skin test; QFT-G: QuantiFERON-TB Gold In Tube assay; INH: isoniazid; BCG: bacille Calmette-Guerin; SD: standard deviation

ISSN: 1745-6673