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Table 2 Exposure to chlorinated and aromatic hydrocarbons and lymphoma in total (n = 710 matched pairs)

From: Solvent exposure and malignant lymphoma: a population-based case-control study in Germany

  Cases Controls Adj. ORa 95% CI
  N % N %   
CHLORINATED HYDROCARBONS       
Chlorinated hydrocarbons in total [ppm*yrs.]       
   0 ppm*yrs. 567 79.9 563 79.3 1.0 -
   >0, <= 4.4 ppm*yrs. 53 7.5 74 10.4 0.7 0.5–1.0
   >4.4, <= 47.3 ppm*yrs. 54 7.6 59 8.3 0.9 0.6–1.3
   >47.3 ppm*yrs. 29 4.1 14 2.0 2.1 1.1–4.3
Trend test*       P = 0.03
Trichloroethene [ppm*yrs.]       
   0 ppm*yrs. 610 85.9 602 84.4 1.0 -
   >0, <= 4.4 ppm*yrs. 40 5.6 55 7.7 0.7 0.4–1.1
   >4.4, <= 35 ppm*yrs. 32 4.5 44 6.2 0.7 0.5–1.2
   >35 ppm*yrs. 21 3.0 9 1.3 2.1 1.0–4.8
Trend test*       P = 0.14
Tetrachloroethene [ppm*yrs.]       
   0 ppm*yrs. 667 93.9 679 95.6 1.0 -
   >0, <= 9.1 ppm*yrs. 16 2.3 16 2.3 1.1 0.5–2.3
   >9.1, <= 78.8 ppm*yrs. 14 2.0 13 1.8 1.0 0.5–2.2
   >78.8 ppm*yrs. 6 0.8 2 0.3 3.4 0.7–17.3
Trend test*       P = 0.12
Carbon tetrachlorine [ppm*yrs.]       
   0 ppm*yrs. 681 95.9 696 98.0 1.0 -
   >0, <= 2.3 ppm*yrs. 13 1.8 8 1.1 1.9 0.7–5.2
   >2.3, <= 48.1 ppm*yrs. 8 1.1 5 0.7 2.0 0.6–6.9
   >48.1 ppm*yrs. 1 0.1 1 0.1 - -
Trend test*       P = 0.48
Dichloromethane [ppm*yrs.]       
   0 ppm*yrs. 681 95.9 681 95.9 1.0 -
   >0, <= 26.3 ppm*yrs. 8 1.1 16 2.3 0.4 0.2–1.0
   >26.3, <= 175 ppm*yrs. 9 1.3 11 1.5 0.8 0.3–1.9
   >175 ppm*yrs. 5 0.7 2 0.3 2.2 0.4–11.6
Trend test*       P = 0.40
AROMATIC HYDROCARBONS       
Benzene [ppm*yrs.]       
   0 ppm*yrs. 591 83.2 590 83.1 1.0  
   >0, <= 8.6 ppm*yrs. 53 7.5 60 8.5 0.9 0.6–1.3
   >8.6, <= 130 ppm*yrs. 47 6.6 48 6.8 1.0 0.7–1.5
   >130 ppm*yrs. 12 1.7 12 1.7 0.8 0.4–1.9
Trend test*       P = 0.87
Toluene [ppm*yrs.]       
   0 ppm*yrs. 538 75.8 545 76.8 1.0  
   >0, <= 3.5 ppm*yrs. 81 11.4 80 11.3 1.0 0.7–1.5
   >3.5, <= 207 ppm*yrs. 70 9.9 69 9.7 1.1 0.7–1.5
   >207 ppm*yrs. 14 2.0 16 2.3 0.8 0.4–1.7
Trend test*       P = 0.74
Xylene [ppm*yrs.]       
   0 ppm*yrs. 549 77.3 552 77.7 1.0  
   >0, <= 4.4 ppm*yrs. 74 10.4 80 11.3 0.9 0.7–1.3
   >4.4, <= 230 ppm*yrs. 68 9.6 63 8.9 1.1 0.7–1.6
   >230 ppm*yrs. 12 1.7 15 2.1 0.8 0.3–1.6
Trend test*       P = 0.56
Styrene [ppm*yrs.]       
   0 ppm*yrs. 542 76.3 541 76.2 1.0  
   >0, <= 1.5 ppm*yrs. 70 9.9 85 12.0 0.7 0.5–1.0
   >1.5, <= 67.1 ppm*yrs. 79 11.1 67 9.4 1.2 0.8–1.7
   >67.1 ppm*yrs. 12 1.7 17 2.4 0.6 0.3–1.4
Trend test*       P = 0.43
  1. Missing values were included as a separate category (not shown)
  2. a Odds Ratio (OR) adjusted for smoking [packyears] and alcohol consumption [g per day]
  3. * To calculate tests for trend, the exposure scores were included as continuous variables in the logistic regression model
  4. Abbreviations: OR = odds ratio; CI = confidence interval; yrs. = years