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Table 3 Solvent exposure and HL, B-NHL, and T-NHL (unconditional logistic regression analysis)

From: Solvent exposure and malignant lymphoma: a population-based case-control study in Germany

  Contr. HL (n = 116) B-NHL (n = 554) T-NHL (n = 35)
  N N Adj. OR a 95% CI N Adj. OR a 95% CI N Adj. OR a 95% CI
CHLORINATED HYDROCARBONS           
Chlorinated hydrocarbons in total [ppm*yrs.]           
   0 ppm*yrs. 563 101 1.0 - 436 1.0 - 26 1.0 -
   >0, <= 4.4 ppm*yrs. 74 5 0.3 0.1–0.8 45 0.8 0.5–1.2 2 0.5 0.1–2.5
   >4.4, <= 47.3 ppm*yrs. 59 8 0.8 0.3–2.1 42 0.9 0.6–1.4 4 1.5 0.4–5.0
   >47.3 ppm*yrs. 14 1 0.5 0.1–4.6 27 2.4 1.2–4.7 1 1.3 0.1–11.4
Trend test*    p = 0.63 (neg.)    p = 0.02    p = 0.23  
Trichloroethene [ppm*yrs.]           
   0 ppm*yrs. 602 10.4 1.0 - 47+ 1.0 - 27 1.0 -
   >0, <= 4.4 ppm*yrs. 55 6 0.4 0.2–1.1 32 0.7 0.5–1.2 2 0.7 0.2–3.3
   >4.4, <= 35 ppm*yrs. 44 3 0.4 0.1–1.4 27 0.8 0.5–1.3 2 1.1 0.2–5.1
   >35 ppm*yrs. 9 2 2.0 0.4–10.5 17 2.3 1.0–5.3 2 4.7 0.8–26.1
Trend test*    p = 0.97    p = 0.08    p = 0.09  
Tetrachloroethene [ppm*yrs.]           
   0 ppm*yrs. 679 111 1.0 - 521 1.0 - 30 1.0 -
   >0, <= 9.1 ppm*yrs. 16 3 1.7 0.4–6.9 12 0.9 0.4–2.0 1 1.7 0.2–14.4
   >9.1, <= 78.8 ppm*yrs. 13 1 0.7 0.1–6.3 12 1.0 0.5–2.3 1 1.5 0.2–12.5
   >78.8 ppm*yrs. 2 - - - 5 3.2 0.6–16.7 1 - -
Trend test*    p = 0.74 (neg.)    p = 0.16    p = 0.01  
CTET [ppm*yrs.]           
   0 ppm*yrs. 696 113 1.0 - 530 1.0 - 33 1.0 -
   >0, <= 2.3 ppm*yrs. 8 1 0.8 0.1–8.5 12 1.8 0.7–4.6 - - -
   >2.3, <= 48.1 ppm*yrs. 5 1 3.7 0.4–33.6 7 1.5 0.5–4.8 - - -
   >48.1 ppm*yrs. 1 - - - 1 - - - - -
Trend test*    p = 0.86 (neg.)    p = 0.60   - - -
DCM [ppm*yrs.]           
   0 ppm*yrs. 681 113 1.0 - 531 1.0 - 32 1.0 -
   >0, <= 26.3 ppm*yrs. 16 2 0.7 0.2–3.6 6 0.4 0.2–1.1 - - -
   >26.3, <= 175 ppm*yrs. 11 - - - 8 0.9 0.3–2.3 1 1.2 0.1–10.9
   >175 ppm*yrs. 2 - - - 5 2.7 0.5–14.5 - - -
Trend test*    p = 0.24 (neg.)    p = 0.29    p = 0.5 (neg.)
AROMATIC HYDROCARBONS           
Benzene [ppm*yrs.]           
   0 ppm*yrs. 590 101 1.0 - 459 1.0 - 26 1.0 -
   >0, <= 8.6 ppm*yrs. 60 9 1.0 0.4–2.3 41 0.9 0.6–1.4 3 1.2 0.3–4.4
   >8.6, <= 130 ppm*yrs. 48 5 0.9 0.3–2.5 39 1.0 0.6–1.5 3 1.7 0.5–6.1
   >130 ppm*yrs. 12 - - - 11 1.0 0.4–2.3 1 1.7 0.2–15.0
Trend test*    P = 0.22 (neg.)     P = 0.50    P = 0.83
Toluene [ppm*yrs.]           
   0 ppm*yrs. 545 88 1.0 - 421 1.0 - 24 1.0 -
   >0, <= 3.5 ppm*yrs. 80 19 1.2 0.7–2.3 56 1.0 0.7–1.5 6 1.6 0.6–4.4
   >3.5, <= 207 ppm*yrs. 69 8 0.9 0.4–2.0 60 1.1 0.8–1.6 2 0.8 0.2–3.5
   >207 ppm*yrs. 16 - -   13 0.9 0.4–2.0 1 1.3 0.2–1.6
Trend test*    P = 0.30 (neg.)     P = 0.43    P = 0.72
Xylene [ppm*yrs.]           
   0 ppm*yrs. 552 88 1.0 - 432 1.0 - 24 1.0 -
   >0, <= 4.4 ppm*yrs. 80 20 1.4 0.7–2.6 48 0.8 0.5–1.2 6 1.7 0.6–4.7
   >4.4, <= 230 ppm*yrs. 63 8 0.8 0.3–2.0 59 1.2 0.8–1.7 2 0.8 0.2–3.6
   >230 ppm*yrs. 15 - - - 11 0.9 0.4–1.9 1 1.5 0.2–13.0
Trend test*    P = 0.31 (neg.)     P = 0.34    P = 0.63
Styrene [ppm*yrs.]           
   0 ppm*yrs. 541 91 1.0 - 423 1.0 - 23 1.0 -
   >0, <= 1.5 ppm*yrs. 85 11 0.4 0.2–0.8 53 0.8 0.6–1.2 6 1.3 0.5–3.6
   >1.5, <= 67.1 ppm*yrs. 67 13 1.5 0.7–3.1 62 1.2 0.8–1.7 4 1.6 0.5–4.8
   >67.1 ppm*yrs. 17 - - - 12 0.8 0.4–1.8 - - -
Trend test*    P = 0.26 (neg.)     P = 0.18    P = 0.41 (neg.)
  1. Missing values were included as a separate category (not shown)
  2. a Odds Ratio (OR) adjusted for age, sex, region, smoking [packyears] and alcohol consumption [g per day]
  3. * To calculate tests for trend, the exposure scores were included as continuous variables in the logistic regression model; (neg.) means: p for trend for a negative association