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Table 2 Characteristics of KNR epidemiological studies by treatment of worker exposure

From: New views on the hypothesis of respiratory cancer risk from soluble nickel exposure; and reconsideration of this risk's historical sources in nickel refineries

First Author (Year) Follow up period Year first employed Number of workers Cases of lung cancer Qualifications for study entrya
I. Studies using rule based allocation of workers to process department
Pedersen (1973) [1]b 1953–71 1910–60 1,916 48 ≥ 3 years employment; alive on Jan. 1, 1953
Magnus (1982) [2]b 1953–79 1916–65 2,247 82 ≥ 3 years employment; alive on Jan. 1, 1953
II. Studies using ICNCM Job Exposure Matrix developed by protocol
ICNCM (1990)[3]b 1953–84 1946–69 3,250 77 ≥ 1 year employment; alive on Jan. 1, 1953
Andersen (1996) [4]b 1953–93 1916–40 379 203 ≥ 3 years employment; alive on Jan. 1, 1953
   1946–83 4,385   ≥ 1 year employment; alive on Jan. 1, 1953
III. Studies using revised Job Exposure Matrix
Grimsrud (2002)[6]c Dec '52-Aug '95 1910–94 5,389 227 ≥ 1 year employment; alive on Jan. 1, 1953
Grimsrud (2003)[7]b 1953–2000 1910–89 5,297 267 ≥ 1 year employment; alive on Jan. 1, 1953
Grimsrud (2005)[8]c Dec '52-Aug '95 1910–94 5,389 227 ≥ 1 year employment; alive on Jan. 1, 1953
  1. a A worker qualified on Jan. 1, 1953, or on the first succeeding date when he had the minimum qualifying employment. b Cohort study
  2. c Case control study
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