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Figure 4 | Journal of Occupational Medicine and Toxicology

Figure 4

From: Inhibition of gap junctional Intercellular communication in WB-F344 rat liver epithelial cells by triphenyltin chloride through MAPK and PI3-kinase pathways

Figure 4

Effect of LY294002 (PI3K inhibitor) on TPTC-induced disruption of GJIC in WB-F344 cells (mean values ± S.D.). The control group comprises negative controls. The LY294002 group comprises cells treated with.100 μM LY294002 for 30 min. The TPTC group comprises cells treated with 1.5 ppm TPTC for 30 min. The LY294002 + TPTC group comprises cells pre-treated with 100 μM LY294002 and exposed to 1.5 ppm TPTC for 30 min. Asterisks indicate statistically significant difference. (# p < 0.05 compared with the control group, * p < 0.05 compared with the group exposed to LY294002 alone, and p < 0.05 compared with the group exposed to TPTC alone.)

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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673