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Table 1 ABR thresholds to broadband clicks.

From: Uniform comparison of several drugs which provide protection from noise induced hearing loss

Group

Initial

threshold

Final

threshold

PTS

P

Saline + oil (control) (n = 10)

58.75 ± 6.07

82.75 ± 7.52

24.16 ± 9.25

< 0.001

NAC (n = 10)

57.0 ± 6.74

73.5 ± 11.06

16.5 ± 8.51

< 0.001

Furosemide (n = 10)

61.0 ± 3.94

74.5 ± 7.61

13.5 ± 5.29*

< 0.001

Furosemide + NAC (n = 10)

59.0 ± 6.14

74.0 ± 8.75

15.0 ± 7.45*

< 0.001

Furosemide + ACE +Mg

(n = 6)

58.33 ± 6.06

76.67 ± 7.53

18.33 ± 5.16

< 0.001

ACE + Mg

(n = 7)

55.0 ± 5.47

69.54 ± 9.86

14.54 ± 9.34*

< 0.001

  1. Mean ± SD of ABR thresholds to broadband clicks in dB pe SPL and the threshold shifts (PTS) in dB and the number of mice in each group tested. The results of two-tailed t-tests with Bonferroni correction comparing initial and final thresholds are shown (in the column of P). PTS in the groups marked * were significantly different from that in the control group - i.e. provided protection.