Skip to main content

Table 1 ABR thresholds to broadband clicks.

From: Uniform comparison of several drugs which provide protection from noise induced hearing loss

Group Initial
threshold
Final
threshold
PTS P
Saline + oil (control) (n = 10) 58.75 ± 6.07 82.75 ± 7.52 24.16 ± 9.25 < 0.001
NAC (n = 10) 57.0 ± 6.74 73.5 ± 11.06 16.5 ± 8.51 < 0.001
Furosemide (n = 10) 61.0 ± 3.94 74.5 ± 7.61 13.5 ± 5.29* < 0.001
Furosemide + NAC (n = 10) 59.0 ± 6.14 74.0 ± 8.75 15.0 ± 7.45* < 0.001
Furosemide + ACE +Mg
(n = 6)
58.33 ± 6.06 76.67 ± 7.53 18.33 ± 5.16 < 0.001
ACE + Mg
(n = 7)
55.0 ± 5.47 69.54 ± 9.86 14.54 ± 9.34* < 0.001
  1. Mean ± SD of ABR thresholds to broadband clicks in dB pe SPL and the threshold shifts (PTS) in dB and the number of mice in each group tested. The results of two-tailed t-tests with Bonferroni correction comparing initial and final thresholds are shown (in the column of P). PTS in the groups marked * were significantly different from that in the control group - i.e. provided protection.