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Table 2 ABR thresholds to 8 kHz tone bursts.

From: Uniform comparison of several drugs which provide protection from noise induced hearing loss

Group Initial Threshold Final Threshold PTS P
Saline + oil (control) (n = 10) 57.08 ± 8.64 83.33 ± 6.15 26.25 ± 9.56 < 0.001
NAC (n = 10) 55.0 ± 9.42 72.0 ± 10.32 17.0 ± 10.05* < 0.001
Furosemide (n = 10) 62.0 ± 5.09 81.5 ± 7.09 19.5 ± 8.64* < 0.001
Furosemide + NAC (n = 10) 55.5 ± 6.43 76.0 ± 7.37 20.5 ± 8.95* < 0.001
Furosemide + ACE +Mg
(n = 6)
58.33 ± 5.16 82.50 ± 6.89 24.17 ± 3.76 < 0.001
ACE + Mg
(n = 7)
53.63 ± 8.09 76.81 ± 12.50 23.18 ± 12.30 < 0.001
  1. Mean ± SD of ABR thresholds to 8 kHz tone bursts in dB pe SPL and the threshold shifts (PTS) in dB and the number of mice in each group tested. The results of two-tailed t-tests with Bonferroni correction comparing initial and final thresholds are shown (in the column of P). PTS in the groups marked * were significantly different from that in the control group - i.e. provided protection.