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Table 2 ABR thresholds to 8 kHz tone bursts.

From: Uniform comparison of several drugs which provide protection from noise induced hearing loss

Group

Initial Threshold

Final Threshold

PTS

P

Saline + oil (control) (n = 10)

57.08 ± 8.64

83.33 ± 6.15

26.25 ± 9.56

< 0.001

NAC (n = 10)

55.0 ± 9.42

72.0 ± 10.32

17.0 ± 10.05*

< 0.001

Furosemide (n = 10)

62.0 ± 5.09

81.5 ± 7.09

19.5 ± 8.64*

< 0.001

Furosemide + NAC (n = 10)

55.5 ± 6.43

76.0 ± 7.37

20.5 ± 8.95*

< 0.001

Furosemide + ACE +Mg

(n = 6)

58.33 ± 5.16

82.50 ± 6.89

24.17 ± 3.76

< 0.001

ACE + Mg

(n = 7)

53.63 ± 8.09

76.81 ± 12.50

23.18 ± 12.30

< 0.001

  1. Mean ± SD of ABR thresholds to 8 kHz tone bursts in dB pe SPL and the threshold shifts (PTS) in dB and the number of mice in each group tested. The results of two-tailed t-tests with Bonferroni correction comparing initial and final thresholds are shown (in the column of P). PTS in the groups marked * were significantly different from that in the control group - i.e. provided protection.