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Table 1 Summary of experimental groups, intensity and rise time of impulse noise, degree of threshold shift and possible protection by furosemide

From: Effects of furosemide on the hearing loss induced by impulse noise

 

Noise

   
 

Intensity

(dB SPL)

Presumed

rise time

(μsec)

TS

(dB)

Furosemide

protection

Explanation

(see text for

details)

Simulated MI6; sound effects site

Experiment

Ia - Computer speaker (mice)

123

>88

NS

NA

Intensity too low

Ib - Power amplifier, very large speaker (Psammomys)

155

>>88

NS

NA

Rise time too slow

II - 20W speaker (mice)

135

>88

11.9

Total

Active displacements reduced by furosemide

III - Small exposure chamber (mice)

155

>88

22.5

Total

Active displacements reduced by furosemide

Actual M16; firing range

IV - Actual M16; firing range (mice)

155

88

13.7

None

Tearing damage; furosemide not effective

  1. NS - not significant
  2. NA - not applicable