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Figure 1 | Journal of Occupational Medicine and Toxicology

Figure 1

From: Occupational airborne exposure, specific sensitization and the atopic status: evidence of a complex interrelationship

Figure 1

A. Pathomechanic scheme of work-related asthma. Specific sensitization and atopy represent response variables of the main risk variable ‘occupational exposure’ as well as explanatory variables of the definite response variable ‘work-related asthma’. For details see text. 1) Broadening of sensitization to related allergens. B. Pathomechanic scheme of allergic asthma. Specific sensitization as a main mechanism of work-related asthma by exposure to high molecular latex allergens. The structural relations between factors are simplified in the case of a main pathomechanism. C. Pathomechanic scheme of isocyanate asthma. The main pathomechanism is unknown. The schema of Figure 1A cannot be principally simplified.

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