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Table 2 Distribution of sensitization to common allergens in the latex and MDI subgroups according to duration of exposure

From: Occupational airborne exposure, specific sensitization and the atopic status: evidence of a complex interrelationship

 

Latex-exposed subjects (n = 184)

MDI-exposed subjects (n = 156)

P values

 

All n = 184

Latex sensitized+n = 145 (78.8%)

Latex non-sensitized n = 39 (21.2%)

All n = 156

MDI sensitized+n = 20 (12.8%)

MDI non-sensitized n = 136 (87.2%)

 

Age (mean); years

32.5

31.6

35.8

41.4

41.5

41.4

 

M/W

18 /166

15 /130

3 /36

139 /17

15 /5

124 /12

 

Exposure duration; mean (median) years

11.4 (9)

10.8 (9)

13.6 (11)

16.5 (14)

16.8 (18)

16.5 (13)

 

Exposure groups; n (%)

168 (100)

131 (78)

37 (22)

152 (100)

19 (12.5))

133 (87.5)

 

Exposure = < 7 years

62 (36.9)

52/62 (83.9)

10/62 (16.1)

43 (28.3)

2/ 43 (4.6)

41/ 43 (95.4)

 

7 years < exposure = < 15 years

66 (39.3)

53/66 (80.3)

13/66 (19.7)

39 (25.6)

6/39 (15.4)

33/39 (84.6)

 

Exposure > 15 years

40 (23.8)

26/40 (65)

14/40 (35)

70 (46.1)

11/70 (15.7)

59/70 (84.3)

 

Atopy category 1; n (%)

75/184 (40.7)

65/145 (44.8)

10 /39 (25.6)

54/156 (34.6)

3/20 (15)

51/136 (37.5)

**

Exposure = < 7 years

23/62 (37.1)

22/52 (42.3)

1/10 (10)

20/43(46.5)

1/2

20/41 (48.8)

 

7 years < exposure = < 15 years

29/66 (43.9)

25/53 (47.2)

4/13 (30.7)

15/39 (38.5)

1 /6

14/33 (42.4)

 

exposure > 15 years

17/40 (42.5)

12/26 (46.2)

5/14 (35.7)

17/70 (24.2)

1/ 11

15/59 (25.4)

 

Atopy category 2; n (%)

46/184 (25.0)

43/145 (29.7)

3/39 (7.7)

29/156 (18.6)

0

29/136 (21.3)

***

exposure = < 7 years

12/62 (19.3)

12/52 (23.1)

0/10 (0)

10/43 (23.2)

-

10/41 (24.4)

 

7 years < exposure = < 15 years

20/66 (30.3)

19/53 (35.8)

1/13 (7.7)

9/39 (23.1)

-

9/33 (27.2)

 

Exposure > 15 years

10/40 (25)

8/26 (30.8)

2/14 (14.3)

7/70 (10)

-

8/59 (13.6)

 

Total IgE mean (median), kU/L #

286.3 (105.7)

334.3 (168)

73.4 (29.3)

171.6 (74)

135.0 (77.3)

176.5 (74)

 

Exposure = < 7 years

329.7 (130.5)

373.5 (169)

101.7(23.2)

187.3 (95.7)

246.6 (246.6)

184.1 (95.7)

 

7 years < exposure = < 15 years

264.3 (116)

309.9 (165.5)

81.7 (49.9)

205.1 (69)

97.7 (64.5)

223.4 (70.3)

 

Exposure > 15 years

231.6 (91.4)

329.3 (151.5)

50.2 (33)

118.0 (64.5)

131.1 (88.4)

115.5 (60)

 

Total IgE elevated; n (%)

94/182 (51.6)

89/143 (62.2)

5/39 (12.8)

60/144 (41.8)

9/19 (47.4)

51/125 (40.8)

**

Exposure = < 7 years

33/62 (53.2)

32/52 (61.5)

1/10 (10)

19/40 (47.5)

1/2 (50)

18/38 (47.4)

 

7 years < exposure = < 15 years

36/65 (55.4)

34/52 (65.4)

2/13

14/34 (41.2)

2/5 (40)

12/29 (41.4)

 

Exposure > 15 years

18/40 (45)

16/26 (61.5)

2/14

25/68 (36.8)

5/11 (45.4)

20/57 (35.1)

 
  1. + Sensitized = specific IgE antibodies detected.
  2. # In 2 subjects of the latex group (both sensitized) and in 12 subjects of the MDI group (1 sensitized, 11 non-sensitized the total IgE level could not be measured.
  3. P values are presented for exposure differences (latex vs. MDI) in odds ratios relating specific sensitization and atopy (Mantel-Haenszel statistics).
  4. *** p < 0.001; ** p < 0.005; * p < 0.05.