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Table 1 Baseline characteristics of participants and dropouts at T0 (n = 49)

From: Diisocyanate-induced asthma in Switzerland: long-term course and patients’ self-assessment after a 12-year follow-up

 

Participants (n = 35)

Dropouts (n = 14)

p-value

Age at diagnosis

39 ± 13

36 ± 13

0.53

Sex (males)

33 (94%)

14 (100%)

1.0

FVC% predicted

102 ± 17

97 ± 13

0.37

FEV1% predicted

91 ± 16

90 ± 16

0.89

FEV1/FVC

75 ± 9

74 ± 10

0.50

PD20 (mg)

0.95 (1.7)

0.30 (0.5)

0.03

NSBHR positivity

23 (68%)

11 (92%)

0.13

Total exposure time (months)

51 (104)

74 (89)

0.77

Time with symptoms (months)

12 (26)

24 (31)

0.38

Smokers

10 (29%)

6 (43%)

0.5

Pack-years*

25 (24)

13 (14)

0.16

Upper airway symptoms

28 (80%)

11 (79)

1.0

Asthma symptoms

34 (97%)

14 (100)

1.0

Asthma medication

31 (91%)

8 (89)

1.0

  1. Legend: FVC = forced expiratory vital capacity. FEV1 = forced expiratory volume in 1 second. NSBHR = nonspecific bronchial hyperreactivity. PD20 = provocative dose of methacholine producing a fall in FEV1 of 20%. *Pack-years for smokers and ex-smokers added. Data is presented as mean ± SD, median and interquartile range (IQR) or number (%).