Skip to main content

Table 1 Baseline characteristics of participants and dropouts at T0 (n = 49)

From: Diisocyanate-induced asthma in Switzerland: long-term course and patients’ self-assessment after a 12-year follow-up

  Participants (n = 35) Dropouts (n = 14) p-value
Age at diagnosis 39 ± 13 36 ± 13 0.53
Sex (males) 33 (94%) 14 (100%) 1.0
FVC% predicted 102 ± 17 97 ± 13 0.37
FEV1% predicted 91 ± 16 90 ± 16 0.89
FEV1/FVC 75 ± 9 74 ± 10 0.50
PD20 (mg) 0.95 (1.7) 0.30 (0.5) 0.03
NSBHR positivity 23 (68%) 11 (92%) 0.13
Total exposure time (months) 51 (104) 74 (89) 0.77
Time with symptoms (months) 12 (26) 24 (31) 0.38
Smokers 10 (29%) 6 (43%) 0.5
Pack-years* 25 (24) 13 (14) 0.16
Upper airway symptoms 28 (80%) 11 (79) 1.0
Asthma symptoms 34 (97%) 14 (100) 1.0
Asthma medication 31 (91%) 8 (89) 1.0
  1. Legend: FVC = forced expiratory vital capacity. FEV1 = forced expiratory volume in 1 second. NSBHR = nonspecific bronchial hyperreactivity. PD20 = provocative dose of methacholine producing a fall in FEV1 of 20%. *Pack-years for smokers and ex-smokers added. Data is presented as mean ± SD, median and interquartile range (IQR) or number (%).