Table 1 Sources and major antigens of extrinsic allergic alveolitis (hypersensitivity pneumonitis)
From: Spotlight on the diagnosis of extrinsic allergic alveolitis (hypersensitivity pneumonitis)
Disease | Causative exposure | Antigens |
|---|---|---|
Farmer's lung | Mouldy hay | Saccharopolyspora rectivirgula (Micropolyspora faeni), Thermoactinomyces vulgaris, Aspergilli |
Bagassosis | Mouldy sugar cane fiber | Thermoactinomyces sacchari |
Humidifier/air-conditioner lung | Contaminated forced-air systems, heated water reservoirs | S. rectivirgula, T. vulgaris, various fungi |
Bird breeder's lung | Pigeons, parakeets, fowl | Avian proteins (of bloom or faeces) |
Metal working hypersensitivity pneumonitis | Microbially contaminated metal working fluid | Various moulds and bacteria |
Cheese worker's lung | Cheese mould | Penicillium casei |
Malt worker‘s lung | Mouldy malt | Aspergillus clavatus |
Paprika splitter‘s lung | Paprika dust | Mucor stolonifer |
Mollusk shell hypersensitivity | Shell dust | Proteins in dust from sea snail shells or mother-of-pearl shells |
Chemical worker’s lung, isocyanate alveolitis | Manufacture of plastics, polyurethane foam, rubber | Trimellitic anhydride, diisocyanates |