Diesel engine exhaust and lung cancer risks – evaluation of the meta-analysis by Vermeulen et al. 2014

Table 12 Joint analysis of Garshick et al. [3] (modified coefficients), Silverman et al. [4] and Möhner et al. [17] (adapted)

	Coef.	P	95 % CI
Fixed effects, adjusted	0.00054	0.14 (0.083)	−0.00026 (−0.00007	0.00133 0.00115)
Random intercept, scaled	0.00024	0.36	−0.00027	0.00074
Greenland/Longnecker method	0.00032	0.035	0.00002	0.00062
Crump et al. [14], REC4
Fixed effects, adjusted	0.00020	0.35 (0.30)	−0.00029 (−0.00018	0.00069 0.00058)
Random intercept, scaled	0.00010	0.11	−0.00002	0.00022
Greenland/Longnecker method	0.00015	0.31	−0.00014	0.00044
Crump et al. [14], REC6
Fixed effects, adjusted	0.00013	0.33 (0.28)	−0.00018 (−0.00010	0.00042 0.00035)
Random intercept, scaled	0.000073	0.025	0.00001	0.00014
Greenland/Longnecker method	0.00012	0.44	−0.00019	0.00043

Comparison of the estimated effect for the cumulative exposure to log RR, calculated with various regression methods. Coefficient (Coef.) of the cumulative exposure (Dose) to DEE in μg/m³-years, corresponding P-value and 95 % confidence interval for the coefficient, 95 % CI. The figures in parentheses are the results when using the standard normal distribution in the model with fixed effects. Silverman et al. [4] was incorporated as used by Vermeulen et al. [1], and in accordance with the re-analysis by Crump et al. [14] with adjustment for radon exposure (REC4, REC6, cf. Table 3)

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