Diesel engine exhaust and lung cancer risks – evaluation of the meta-analysis by Vermeulen et al. 2014

Table 3 Re-analysis of Silverman et al. [4] with adjustment for radon exposure (Crump et al. [14], Table 3)

Exposure category	Average dose	Lower dose	Upper dose	OR	95 % CI		Number of persons	Number of cases
					Lower	Upper
Crump et al. [14], REC4
Reference	0.71	0	<4.9	1	1	1	217	49
Cat 1	26.65	4.9	<70.4	0.80	0.41	1.55	266	50
Cat 2	243.43	70.4	<498.4	1.67	0.73	3.81	192	49
Cat 3	1522.10	-	≥498.4	1.50	0.54	4.17	189	50
Crump et al. [14], REC6
Reference	0.61	0	<2.8	1	1	1	230	49
Cat 1	20.47	2.8	<50.6	1.07	0.57	2.00	247	50
Cat 2	158.27	50.6	<388.0	1.35	0.62	2.94	206	49
Cat 3	1156.89	-	≥388.0	1.43	0.52	3.94	181	50

The results are based on the exposure metrics REC4 and REC6 with a lag of 15 years (see text). Dose refers to the cumulative exposure to DEE in μg/m³-years. For every category (Reference, Cat 1, Cat 2, Cat 3), averages and the lower and upper limits of the dose are specified. Odds ratio OR with 95 % confidence intervals (95 % CI) and the number of persons observed and the number of lung cancer deaths per dose category are reported

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