Fig. 8

Bio-plex ELISA of mouse serum. Serum was collected by collecting blood via cardiac puncture and then briefly centrifuging to remove cells from exposed and unexposed WT and TLR9^−/− mice (n = 6). ELISA was done with antibodies to IL-1β, IL-6, IL-10, IL-12, IFNγ, and TNFα. IFNγ was significantly reduced after 1 and 5 days exposure in TLR9^−/− mice compared to WT (*** = p ≤ 0.01)