Fig. 4From: An evaluation of the protective role of vitamin C in reactive oxygen species-induced hepatotoxicity due to hexavalent chromium in vitro and in vivoVit C inhibited ROS accumulation. a The hepatocytes were treated with different concentrations of Vit C (0–2430 μM) for 2 h and then analyzed for cell survival rate. (B-C) The L-02 hepatocytes were pretreated with Vit C (200 μM) for 2 h and then were exposed to Cr (VI) (8 and 16 μM) for 24 h. ROS production assay (b) and intracellular superoxide anion production assay (c) were conducted. Data represent mean ± SD. *p < 0.05, compared with the control groupBack to article page