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Table 3 Longitudinal associations between shift work at baseline and diurnal cortisol pattern at follow-up (N = 70)

From: Impact of shift work on the diurnal cortisol rhythm: a one-year longitudinal study in junior physicians

Cortisol slope

Model I

Model II

Model III

Model IV

Model V

Shift work: No

0

0

0

0

0

Shift work: Yes

−0.09 (− 0.18, − 0.01)*

−0.11 (− 0.20, − 0.02) *

−0.11 (− 0.20, − 0.02)*

−0.12 (− 0.21, − 0.04)**

−0.12 (− 0.21, − 0.03)**

Total cortisol AUC

Model I

Model II

Model III

Model IV

Model V

Shift work: No

0

0

0

0

0

Shift work: Yes

5.36 (0.20, 10.52) *

6.19 (1.13, 11.25) *

6.33 (1.25, 11.41) *

6.71 (1.55, 11.86) *

6.64 (1.48, 11.79) *

  1. Linear regression, β (95% CI), *p < 0.05, **p < 0.01
  2. Model I: adjustment for biological factors (age and gender)
  3. Model II: Model I + additional adjustment for work factors (professional tenure and working hours) at baseline
  4. Model III: Model II + additional adjustment for family factors (partnership and children) at baseline
  5. Model IV: Model III + additional adjustment for behavioral factors (smoking, risky alcohol use, physical activity, overweight and obesity) at baseline
  6. Model V: Model IV + additional adjustment for cortisol secretion at baseline