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Table 1 Characteristics of enrolled subjects

From: Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis

Values

Patients with silicosis (A group)

Healthy controls (B group)

P value

N = 18

%

N = 21

%

 

Age(year)

56.7 ± 6.98

50.2 ± 8.32

0.35

Education level

 Elementary school(n)

3

4

 

 Junior high school(n)

15

14

 

 University or beyond(n)

0

3

0.43

Resident

 Urban

2

15

 

 Agrarian

16

6

0.06

Smoking

   

 Smoker

3

10

 

 Non-smoking

10

5

 

 Ex-smoker

5

6

0.17

Ethnicity

 Han nationality

16

18

 

 Minority

2

3

0.45

Marital status

 Married(n)

14

17

 

 Single/divorced/separated(n)

4

4

0.28

Occupation

 Machine operator(n)

5

  

 Mining operator(n)

11

  

 Metalworking(n)

2

  

 Administrator(n)

 

10

 

Office worker(n)

 

11

0.04

BMI(kg/m2)

21.64 ± 7.5

22.7 ± 5.43

0.59

Silicosis phase

I

14

70

   

II

6

30

   

Symptoms lasting time before diagnosis(Month)

 

11 ± 5

    

Silica level

< 0.05 mg/m3

3

15

   

> 0.05 mg/m3

17

85

   

Fung function

FVC(L)

2.44 ± 0.58

 

4.05 ± 0.89

 

0.04*

 

FEV1(L)

2.45 ± 0.64

 

3.37 ± 1.01

 

0.04*

 

MVV(L)

86.2 ± 6.47

 

121.3 ± 7.26

 

0.04*

X-ray result

Slight lung fibrosis

8

40

   

Severe lung fibrosis

12

60

   

Platelet(10 × 9/L)

 

232.5 ± 51.9

 

234.6 ± 67.4

 

0.79

WBC(10 × 9/L)

 

5.53 ± 2.9

 

5.79 ± 3.04

 

0.58

Hb(g/L)

 

115.5 ± 49.4

 

139.2 ± 39.5

 

< 0.01

  1. WBC white blood cell, Hb hemoglobin, FVC forced vital capacity, FEV1 forced expiratory volume in the first second. MVV: maximueP value for age and BMI was evaluated by pearson chi-square test
  2. * p<0.05
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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673