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Table 2 Cancer cases and controls per dose category and scenario with associated lung cancer ORs and corresponding 95% CIs

From: The riddle of shiftwork and disturbed chronobiology: a case study of landmark smoking data demonstrates fallacies of not considering the ubiquity of an exposure

 

Most recent regular amount of cigarettes smoked per day before the onset of illness

  

≤ 20

>  20

OR

95% CI

S1

Controls

538

84

  

Cases

479

168

2.25

1.67–3.04

S2

Controls

609

13

  

Cases

615

32

2.44

1.23–5.11

S3

Controls

609

13

  

Cases

639

8

0.59

0.21–1.54

 

≤ 10

>  10

  

S4

Controls

348

274

  

Cases

283

364

1.63

1.3–2.05

S5

Controls

538

84

  

Cases

479

168

2.25

1.67–3.04

S6

Controls

538

84

  

Cases

581

66

0.73

0.51–1.04

  1. S1 & S4: cumulative smoking at work + at play
  2. S2 & S5: cumulative smoking at work assuming even distribution between at work + at play
  3. S3 & S6: cumulative smoking at work assuming uneven distribution between at work + at play for cases (75% cases in each Table 1 category with 40% of smoking at work; 25% cases in each Table 1 category with 50% at work) and an even distribution for controls