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Table 4 Oxidative stress markers in not-exposed subjects and occupationally exposed group

From: Occupational exposure to organophosphorus and carbamates in farmers in La Cienega, Jalisco, Mexico: oxidative stress and membrane fluidity markers

 

Unexposed Group

(n = 93)

Group A

(n = 25)

Group B

(n = 26)

Group C

(n = 19)

Group D

(n = 22)

P-Value*

GSH (μmol/mL)

1.58 ± 0.6080

0.0027 ± 0.0019

0.0023 ± 0.0086

0.0026 ± 0.0017

0.0026 ± 0.0018

(F = 126.20,

p = 0.000)

GSSG (μmol/mL)

0.5221 ± 0.5900

0.0007 ± 0.0004

0.0009 ± 0.0034

0.0006 ± 0.0003

0.0009 ± 0.0005

(F = 13.84,

p = 0.000)

GSH/GSSG

3.026 ± 1.0305

3.857 ± 3.75

2.555 ± 2.52

4.333 ± 4.66

2.888 ± 2.6

(F = 0.582, p = 0.710)

Carbonyl groups in proteins (μmol/mL)

13.57 ± 9.3

49.44 ± 25.62

80.05 ± 47.77

47.51 ± 15.95

71.06 ± 41.44

(F = 48.63, p = 0.000)

Nitrates-Nitrites (μmol/mL)

5.06 ± 1.8

59.06 ± 55.33

54.49 ± 42.83

63.01 ± 75.09

45.17 ± 28.0

(F = 22.78, p = 0.000)

Lipoperoxides MDA-4HNE (μmol/mL)

1.59 ± 0.89

4.94 ± 1.90

4.22 ± 1.23

4.85 ± 1.96

5.80 ± 2.16

(F = 65.57, p = 0.000)

Membrane fluidity

0.14 ± 0.04

0.49 ± 0.03

0.49 ± 0.04

0.47 ± 0.02

0.49 ± 0.05

(F = 694.84, p = 0.000)

  1. Data are presented as mean values ± standard deviation
  2. *Value obtained with the one-way ANOVA. The comparison was made between the unexposed group and subgroups A, B, C and D, for each oxidative stress marker