Mortality from Parkinson’s disease and other causes among a workforce manufacturing paraquat: an updated retrospective cohort study

Table 2 Observed numbers of deaths and SMR for selected causes of death among males

*ICD-9*	*Cause of death category*	Observed	England & Wales mortality rates		Local mortality rates^a
*ICD-9*	*Cause of death category*	Observed	SMR	95% CI	SMR	95% CI
001–999	All causes of death	394	0.88*	0.80–0.97	0.77**	0.69–0.85
140–208	All malignant neoplasms	136	0.99	0.83–1.17	0.86	0.72–1.01
160–165	Respiratory system	41	0.98	0.71–1.33	0.77	0.55–1.04
162	Bronchus, trachea and lung	38	0.95	0.68–1.31	0.74	0.52–1.02
320–359	Neurological diseases	5	0.44	0.14–1.03	0.43*	0.14–1.00
332.0	Parkinson’s disease	2	0.60	0.07–2.17	0.67	0.08–2.43
332.0	Parkinson’s disease (mentioned)^b	4	0.67	0.18–1.72	0.68	0.19–1.75
390–398, 402, 404, 410–429	All heart disease	105	0.79*	0.65–0.96	0.70**	0.57–0.88
430–438	Cerebrovascular disease	29	0.92	0.61–1.31	0.84	0.56–1.20
460–519	Non-malignant respiratory disease	50	0.94	0.69–1.23	0.74*	0.55–0.98
800–999	External causes of death	18	1.05	0.62–1.65	0.96	0.57–1.52

* p < 0.05, ** p < 0.01; SMR significantly different from 1.0
^a Halton unitary authority and the 5 surrounding local authorities (district and unitary)
^b Mentioned cause of death (1993–2017), underlying cause of death (1960–1992)

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