Table 5 Generalized linear mixed models for PLR parameters, estimating the effect of exposure (sleep deprivation, alcohol exposure) vs. baseline. Parameters and type of exposure that showed significant effects in the fixed effects model were included. An additional analysis on effects after first or second light pulse was carried out (only significant results are shown)
From: The pupillary light reflex (PLR) as a marker for the ability to work or drive – a feasibility study
Endpoint | Parameter | B | S (B) | p-value |
|---|---|---|---|---|
Latency | Sleep deprivation | 0.98 | 0.92 | 0.29 |
Alcohol exposure | 1.62 | 0.91 | 0.08 | |
Latency after second light pulse | Sleep deprivation | 3.6 | 0.72 | < 0.05 |
Alcohol exposure | 1.75 | 0.71 | < 0.05 | |
Light eyes | −0.89 | 3.0 | 0.77 | |
Half dilatation time | Sleep deprivation | 0.050 | 0.013 | < 0.05 |
Alcohol exposure | −0.044 | 0.013 | < 0.05 | |
Half dilatation time after first light pulse | Sleep deprivation | 0.064 | 0.01 | < 0.05 |
Alcohol exposure | −0.068 | 0.01 | < 0.05 | |
Contraction velocity | Sleep deprivation | 0.001 | 0.002 | 0.71 |
Alcohol exposure | −0.001 | 0.002 | 0.8 | |
Quarter dilatation velocity | Sleep deprivation | −0.02 | 0.01 | 0.29 |
Alcohol exposure | 0.02 | 0.01 | 0.36 |