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Fig. 1 | Journal of Occupational Medicine and Toxicology

Fig. 1

From: Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis

Fig. 1

The expression of Nrf2 and Nrf2-dependent antioxidative genes in silicosis patients PBMCs. A The represent images of Nrf2 expression in PBMCs isolated from silicosis patients and healthy controls by confocal laser scanning microscope. B Semi-quantitative analysis of Nrf2 fluorescence levels in PBMC from the two groups. C The expression of Nrf2 and Nrf2-dependent antioxidative genes in silicosis patients PBMCs by real-time PCR. D Western blot analysis of Nrf2 and Nrf2-dependent proteins levels in silicosis patients PBMCs. E Protein levels of Nrf2 and Nrf2-dependent proteins were quantified using Image J Software. F DEGs related to NRF2 in the development of silicosis. Data are expressed as fold changes relative to the healthy control group. Horizontal line represents the mean fold change. A Yellow arrows: lymphocytes and White: monocytes. B, C, E Error bar indicates mean ± SD (n = 36 per group). * P < 0.05 vs. HC, # P < 0.01 vs. HC

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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673