Long-term visual pathway alterations after elemental mercury poisoning: report of a series of 29 cases

Pastor-Idoate, Salvador; Coco-Martin, Rosa M.; Zabalza, Iratxe; Lantigua, Yrbani; Fernández, Itziar; Pérez-Castrillón, Jose L.; Cuadrado, Ruben; de Lazaro, Jose A.; Morejon, Angela; Dueñas-Laita, Antonio; Pastor, Jose C.

doi:10.1186/s12995-021-00341-z

Journal of Occupational Medicine and Toxicology

Table 5 PRVER in Patients and Control Group

From: Long-term visual pathway alterations after elemental mercury poisoning: report of a series of 29 cases

PRVEP			All patients	Control values	p-values	95% CI	Group 1^a	Control values	p-values	95% CI
P100-Da 60 R Lob	Amplitude (μV)	RE	8.82 ± 4.33	7.29 ± 1.59	0.2852	–	5.05 ± 1.03	7.29 ± 1.59	0.0011	[1.020 to 3.450]
	Amplitude (μV)	LE	8.45 ± 4.36	7.29 ± 1.59	0.4193	–	5.05 ± 1.03	7.29 ± 1.59	0.0011	[1.020 to 3.450]
	Latency (ms)	RE	115.17 ± 10.21	112.6 ± 7.19	0.4684	–	130.9 ± 8.17	112.6 ± 7.19	< 0.0001	[−25,36 to − 11,24]
	Latency (ms)	LE	118.06 ± 9.71	112.6 ± 7.19	0.1127	–	130.9 ± 8.17	112.6 ± 7.19	< 0.0001	[−25,36 to − 11,24]
P100-Da 60 L Lob	Amplitude (μV)	RE	8.88 ± 7.44	6.33 ± 2.40	0.2974	–	5.15 ± 1.02	6.33 ± 2.40	0.1538	–
	Amplitude (μV)	LE	8 ± 3.65	6.33 ± 2.40	0.1872	–	5.15 ± 1.02	6.33 ± 2.40	0.1538	–
	Latency (ms)	RE	114 ± 9.24	111.2 ± 4.80	0.3681	–	132.0 ± 7.09	111.2 ± 4.80	< 0.0001	[−26,39 to − 15,21]
	Latency (ms)	LE	118.47 ± 10.36	111.2 ± 4.80	0.0420	[−14,1 to −0,27]	132.0 ± 7.09	111.2 ± 4.80	< 0.0001	[−26,39 to − 15,21]
P100-Da 30 R Lob	Amplitude (μV)	RE	8.29 ± 3.72	6.29 ± 2.16	0.1179	–	4.40 ± 1.56	6.29 ± 2.16	0.0319	[0,1813 to 3,59]
	Amplitude (μV)	LE	7.44 ± 3.91	6.29 ± 2.16	0.3846	–	4.40 ± 1.56	6.29 ± 2.16	0.0319	[0,1813 to 3,59]
	Latency (ms)	RE	116.79 ± 6.21	112.12 ± 8.02	0.0588	–	134.7 ± 15.6	112.12 ± 8.02	0.0006	[−34,03 to −10,97]
	Latency (ms)	LE	122.38 ± 13.51	112.12 ± 8.02	0.0283	[−19,5 to − 1,16]	134.7 ± 15.6	112.12 ± 8.02	0.0006	[−34,03 to −10,97]
P100-Da 30 L Lob	Amplitude (μV)	RE	7.94 ± 4.01	5.93 ± 2.01	0.1392	–	3.85 ± 1.44	5.93 ± 2.01	0.0128	[0,494 to 3,66]
	Amplitude (μV)	LE	6.48 ± 3.78	5.93 ± 2.01	0.6649	–	3.85 ± 1.44	5.93 ± 2.01	0.0128	[0,494 to 3,66]
	Latency (ms)	RE	117.14 ± 7.45	112.4 ± 7.32	0.0898	–	136.8 ± 22.4	112.4 ± 7.32	0.0039	[−39,96 to −8,84]
	Latency (ms)	LE	122.93 ± 17.36	112.4 ± 7.32	0.0724	–	136.8 ± 22.4	112.4 ± 7.32	0.0039	[−39,96 to −8,84]

Data are presented as mean ± SD or as numbers. PRVF pattern reversal visual evoked potential, P100-Da 60 P100 wave with 60′ checkerboard stimuli, P100-Da 30 P100 wave with 30′ checkerboard stimuli, R Lob right occipital cortex, L Lob left occipital cortex, μV microvolts, RE right eye, LE left eye, CI confidence interval
^aGroup 1 is a subgroup of patients with evident visual disturbances in their visual field test. Patients with concentric constriction (17 eyes) and hemi-field defects (5 eyes) patterns

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