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Fig. 3 | Journal of Occupational Medicine and Toxicology

Fig. 3

From: Healthcare-associated exposure to Borna disease virus 1 (BoDV-1)

Fig. 3

Typical cranial magnetic resonance imaging of early BoDV-1 encephalitis. Left column: T2 weighted imaging (top left) shows discrete, nearly symmetric hyperintensities of the insular ribbon (IR), the posteromedial thalamus (PMT), the caudate head (CH) and the lentiform nucleus (LN). These changes are more easily appreciated on diffusion-weighted imaging (DWI, bottom left), where diffusion restriction in these brain areas is visualized as a hyperintense signal. Right column: T2 weighted imaging (top right) shows progressive T2 hyperintensities of the affected areas with associated parenchymal swelling, somewhat more pronounced on the patient’s left side. No T1 hyperintense signal changes, which are characteristic of late-stage BoDV-1 encephalitis, were present at this time point (bottom right)

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