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Table 1 Baseline demographic and clinical characteristics of the study patients

From: Clinical outcomes and survival following lung transplantation for work-related lung disease: a single-center retrospective cohort study

 

WRLD (n = 33)

IPF (n = 91)

P-value

Age, years

52.5 ± 10.2

61.2 ± 6.7

< 0.001

Body mass index, kg/m2

18.9 ± 3.3

21.6 ± 3.3

0.96

Spontaneous pneumothorax, n (%)

17 (51.5)

2 (2.2)

< 0.001

FVC, %

40.71 ± 14.17

50.28 ± 14.14

0.02

FEV1, %

29.27 ± 13.14

52.68 ± 15.02

0.001

DLCO, %

28.9 ± 9.95

29.19 ± 12.66

0.07

6-minute walk distance, m

138.6 ± 58.7

150.4 ± 69.7

0.33

Left ventricular ejection fraction, %

70.0 ± 5.4

70.8 ± 6.0

0.51

Cardiac index, L/min/m2

2.9 ± 0.67

2.95 ± 0.87

0.88

Invasive mechanical ventilation, n (%)

4 (12.1)

11 (12.1)

0.99

Induction therapy, n (%)

  

0.83

 Basiliximab

14 (42.4)

44 (48.4)

 

 r-ATG

13 (39.4)

45 (49.5)

 

Type of lung transplantation, n (%)

  

0.024

 Single

28 (84.8)

58 (63.7)

 

 Bilateral

5 (15.2)

33 (36.3)

 
  1. DLCO diffusing capacity of the lung for carbon monoxide, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, WRLD work-related lung disease, IPF idiopathic pulmonary fibrosis, r-ATG rabbit antithymocyte globulin