Table 6 Hemodynamic and renal functional parameters at 60 and 180 min hemoperfusion of isolated kidney experimental groups and for the control group CON of living pigs
group | CON | A | B | C | D | E | ||
|---|---|---|---|---|---|---|---|---|
RBF Bloodflow | ml/min*100 g | 60 min | ● | 339.9 | 224.8 | 244.5 | 92.8 | 153.8 |
SD | • | 61.1 | 28.4 | 53.5 | 25.8 | 41.5 | ||
Signif.)* | BB;CC;DD;EE | DD;E | DD;EE | D | ||||
180 min | ● | 363.0 | 241.1 | 285.5 | 107.9 | 160.1 | ||
SD | • | 58.0 | 19.4 | 48.5 | 28.4 | 54.8 | ||
R Organ- Resistance | mmHg/(ml/min*100 g) | 60 min | ● | 0.29 | 0.44 | 0.37 | 1.26 | 0.61 |
SD | • | 0.05 | 0.06 | 0.11 | 0.49 | 0.17 | ||
Signif.)* | BB;C;DD;EE | DD;E | DD;EE | DD | ||||
180 min | ● | 0.28 | 0.4 | 0.29 | 1.01 | 0.61 | ||
SD | • | 0.08 | 0.03 | 0.07 | 0.31 | 0.19 | ||
O2-cons Oxygen- Consumption | μmol/min*100 g | 60 min | ● | 263.9 | 214.3 | 141.6 | 120.8 | 206.4 |
SD | • | 49.4 | 22.3 | 21.6 | 27.6 | 43.5 | ||
Signif.)* | BB;CC;DD;EE | CC;DD | EE | DD | ||||
180 min | ● | 246.4 | 213.6 | 142.9 | 116.2 | 198.9 | ||
SD | • | 39.4 | 22.9 | 19.0 | 27.6 | 36.8 | ||
VU Diuresis | ml/min*100 g | 60 min | 0.87 | 13.4 | 7.2 | 5.1 | 0.7 | 3.0 |
SD | 0.25 | 6.1 | 4.7 | 3.8 | 0.3 | 2.3 | ||
Signif.)* | AA | BB;CC;DD;EE | DD;E | DD;E | DD | |||
180 min | ● | 14.4 | 8.9 | 5.7 | 0.4 | 3.2 | ||
SD | • | 6.2 | 5.1 | 3.2 | 0.3 | 2.4 | ||
Cl crea Creatinine Clearance | ml/min*100 g | 60 min | 76.1 | 59.2 | 27.6 | 25.0 | 1.64 | 16.3 |
SD | 6.2 | 13.9 | 7.5 | 10.6 | 1.26 | 8.2 | ||
Signif.)* | A | BB;CC;DD;EE | DD;EE | DD;E | DD | |||
180 min | ● | 65.9 | 30.5 | 24.1 | 1.04 | 15.2 | ||
SD | • | 10.5 | 4.8 | 7.5 | 0.89 | 9.7 | ||
FF Filtration- Fraction | % | 60 min | ● | 22.5 | 15.7 | 14.9 | 2.7 | 13.3 |
SD | • | 7.2 | 6.7 | 5.3 | 2.5 | 6.4 | ||
Signif.)* | • | B;CC;DD;EE | DD | DD | DD | |||
180 min | ● | 24.8 | 16.4 | 11.7 | 1.1 | 11.9 | ||
SD | • | 7.2 | 2.5 | 3.6 | 1.1 | 7.2 | ||
RF H2O Water- Reabsorption- fraction | % | 60 min | 98.9 | 76.7 | 72.4 | 79.6 | 35.4 | 81.6 |
SD | 0.3 | 9.5 | 12.8 | 13.2 | 31.3 | 17.2 | ||
Signif.)* | AA | DD | DD;E | DD | DD | |||
180 min | ● | 76.0 | 70.9 | 72.6 | 36.1 | 74.4 | ||
SD | • | 11.1 | 15.8 | 23.3 | 31.6 | 30.0 | ||
RF Na Sodium- Reabsorption- fraction | % | 60 min | 99,8 | 82,3 | 83,1 | 86,8 | 38,4 | 88,7 |
SD | 0,1 | 8,1 | 10,4 | 10,3 | 24,5 | 5,8 | ||
Signif.)* | AA | DD | DD | DD | DD | |||
180 min | ● | 80,9 | 79,4 | 81,0 | 46,5 | 89,4 | ||
SD | • | 7,9 | 13,9 | 18,3 | 31,4 | 6,0 | ||
TNa Sodium- Reabsorption | mmol/min*100 g | 60 min | 10,8 | 6,83 | 3,16 | 2,91 | 0,12 | 1,98 |
SD | 1,0 | 2,1 | 1,0 | 1,3 | 0,1 | 1,08 | ||
Signif.)* | AA | BB;CC;DD;EE | DD | DD | DD | |||
180 min | ● | 7,82 | 3,43 | 2,77 | 0,09 | 2,02 | ||
SD | • | 1,6 | 0,7 | 1,0 | 0,1 | 1,1 |