Cancer risk among residents of Rhineland-Palatinate winegrowing communities: a cancer-registry based ecological study

Table 4 Cancer risks (standardized incidence ratios SIR) in men with residence in communities with planted winegrowing areas with the estimated incidence of cancer in the national population of Germany as reference

	Area under wine cultivation > 0, ≤ 5% of community area (1,665,594 PY^†)				Area under wine cultivation > 5, ≤ 20% of community area (1,039,435 PY^†)				Area under wine cultivation > 20% of community area (612,714 PY^†)
ICD-10 code	Observed	Expected	SIR	95% CI	Observed	Expected	SIR	95% CI	Observed	Expected	SIR	95% CI
Head & neck (C00–C14)	369	238.00	1.13	1.01–1.25	188	205.94	0.91	0.79–1.05	94	117.54	0.80	0.65–0.98
Stomach (C16)	241	421.10	0.57	0.50–0.65	166	262.89	0.63	0.54–0.74	92	144.55	0.64	0.51–0.78
Colon, sigmoid & rectum (C18–C21)	1188	1445.33	0.82	0.78–0.87	806	906.16	0.89	0.83–0.95	460	497.93	0.92	0.84–1.01
Trachea, bronchus and lung (C33–C34)	1039	1376.19	0.75	0.71–0.80	530	865.12	0.61	0.56–0.67	232	478.60	0.48	0.42–0.55
Skin, malignant melanoma (C43)	230	257.40	0.89	0.78–1.02	188	160.19	1.17	1.01–1.35	119	91.08	1.31	1.08–1.56
Prostate (C61)	1857	1833.70	1.01	0.97–1.06	1359	1152.26	1.18	1.12–1.24	787	628.58	1.25	1.17–1.34
Testis (C62)	154	164.80	0.93	0.79–1.09	107	101.97	1.05	0.86–1.27	77	61.20	1.26	0.99–1.57
Urinary tract (C64-C66+C68)	330	392.87	0.84	0.75–0.94	206	247.03	0.83	0.72–0.96	107	137.47	0.78	0.64–0.94
Bladder (C67, D09.0, D41.4)	699	718.87	0.97	0.90–1.05	470	451.25	1.04	0.95–1.14	266	246.29	1.08	0.95–1.22
NHL (C82–C85)	197	255.32	0.77	0.67–0.89	130	160.18	0.81	0.68–0.96	81	90.11	0.90	0.71–1.12
Leukaemia (C91–C95)	204	253.60	0.80	0.70–0.92	113	158.75	0.71	0.59–0.86	61	89.49	0.68	0.52–0.88
All malignancies (excluding C44)	7761	8751.69	0.89	0.87–0.91	5024	5493.56	0.91	0.89–0.94	2765	3041.59	0.91	0.88–0.94

^† PY: Person-Years were approximated by population figures: the sum of population at the end of the year in the years under consideration.

ISSN: 1745-6673