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Table 2 Estimates of lung function according to radiological findings.

From: Lung function in asbestos-exposed workers, a systematic review and meta-analysis

 

Overall

Studies with X-ray

Studies with (HR)CT

 

n

Estimate

95% CI

I 2 (%)

n

Estimate

95% CI

I 2 (%)

n

Estimate

95% CI

I 2 (%)

FVC (% predicted)

            

   Normal imaging

15

95.7

93.9-97.3

94.8

9

94.9

92.9-96.9

96.2

6

97.1

94.2-100.1

89.1

   Pleural fibrosis

14

89.0

86.5-91.5

96.1

8

87.1

83.9-90.4

89.5

6

91.6

87.8-95.4

96.8

   Asbestosis

20

86.5

83.7-89.4

98.2

10

84.8

80.8-88.8

98.9

10

88.5

84.3-92.7

95.8

FEV 1 (% predicted)

            

   Normal imaging

14

93.6

90.6-96.5

97.3

8

91.4

87.7-95.1

98.0

6

97.4

92.5-102.2

64.7

   Pleural fibrosis

11

89.2

84.7-93.7

93.7

5

83.9

77.2-90.5

42.0

6

93.7

87.6-99.9

95.8

   Asbestosis

17

85.7

80.6-90.7

98.8

7

85.5

77.8-93.1

99.5

10

85.8

79.2-92.5

80.8

FEV 1 /FVC (% predicted)

            

   Normal imaging

3

96.4

94.3-98.5

86.9

2

97.4

92.5-102.2

64.7

1

94.9

86.8-103.0

-

   Pleural fibrosis

5

95.4

92.7-98.1

68.7

2

93.7

87.6-99.9

95.8

3

96.3

92.6-100.1

68.1

   Asbestosis

8

95.5

94.1-96.9

83.8

3

85.8

79.2-92.5

80.8

5

97.0

95.7-98.3

0.0

  1. Comparison of imaging procedure.
  2. Estimates for forced vital capacity (FVC), forced expiratory volume in the first second (FEV1) and the ratio of both parameters (FEV1/FVC) for each radiological subgroup. Results are shown for all included studies as well as separated according to the radiological method used for the diagnosis (conventional chest X-ray or (high resolution) computed tomography. Estimates are expressed as percent predicted together with confidence interval (CI) and I2 as a measure of heterogeneity, n = number of studies included in each subgroup.
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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673