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Table 3 Hematology and BALF Values of Rats Exposed to CD Gas for 6 Months

From: Six-month low level chlorine dioxide gas inhalation toxicity study with two-week recovery period in rats

Group

Control

Low

High

Analyte

Male

Female

Male

Female

Male

Female

Blood Cell Counts

RBC (102/μl)

1108 ± 85

942 ± 124

1039 ± 111

834 ± 72

1019 ± 117

881 ± 130

WBC (104/μl)

89 ± 20

62 ± 15

94 ± 29

56 ± 18

92 ± 21

63 ± 22

Hb (g/dl)

18.1 ± 1.4

16.8 ± 1.8

17.5 ± 2.2

15.2 ± 1.3

17.1 ± 2.0

16.8 ± 2.6

HTC (%)

54.4 ± 3.8

49.5 ± 5.9

52.1 ± 6.6

44.6 ± 4.0

51.7 ± 6.4

47.3 ± 7.5

PLT (104/μl)

78.4 ± 18.0

92.4 ± 18.7

85.5 ± 20.9

90.9 ± 18.7

93.2 ± 31.2

81.2 ± 19.5

MCH (pg)

16.3 ± 0.4

17.9 ± 0.6

16.8 ± 0.6

18.3 ± 0.8

16.8 ± 0.7

18.3 ± 0.9

NE% (%)

14.9 ± 5.8

12.5 ± 6.5

10.4 ± 3.1

13.7 ± 3.5

17.1 ± 4.8

17.5 ± 6.3

EO% (%)

0.9 ± 0.6

1.2 ± 0.9

0.2 ± 0.4*

0.7 ± 0.6

0.3 ± 0.3*

1.1 ± 0.6

BA% (%)

0.5 ± 0.6

0.5 ± 0.5

0.5 ± 0.4

0.8 ± 0.3

0.5 ± 0.

30.2 ± 0.3

MO% (%)

12.2 ± 4.2

12.5 ± 3.5

8.8 ± 2.4*

13.7 ± 3.0

11.5 ± 4.8

13.1 ± 6.3

LY% (%)

69.3 ± 7.9

71.9 ± 6.6

75.4 ± 5.3

67.9 ± 6.3

68.5 ± 4.8

66.2 ± 8.9

BALF Cell Counts

BC (104/ml)

39.4 ± 45.1

12.5 ± 10.0

27.1 ± 37.6

39.9 ± 18.1*

21.8 ± 13.1

28.4 ± 23.5

WBC% (%)

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

  1. Each value represents mean ± standard deviation of 10 rats
  2. * Significantly different from control, p < 0.05