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Table 3 Hematology and BALF Values of Rats Exposed to CD Gas for 6 Months

From: Six-month low level chlorine dioxide gas inhalation toxicity study with two-week recovery period in rats

Group Control Low High
Analyte Male Female Male Female Male Female
Blood Cell Counts
RBC (102/μl) 1108 ± 85 942 ± 124 1039 ± 111 834 ± 72 1019 ± 117 881 ± 130
WBC (104/μl) 89 ± 20 62 ± 15 94 ± 29 56 ± 18 92 ± 21 63 ± 22
Hb (g/dl) 18.1 ± 1.4 16.8 ± 1.8 17.5 ± 2.2 15.2 ± 1.3 17.1 ± 2.0 16.8 ± 2.6
HTC (%) 54.4 ± 3.8 49.5 ± 5.9 52.1 ± 6.6 44.6 ± 4.0 51.7 ± 6.4 47.3 ± 7.5
PLT (104/μl) 78.4 ± 18.0 92.4 ± 18.7 85.5 ± 20.9 90.9 ± 18.7 93.2 ± 31.2 81.2 ± 19.5
MCH (pg) 16.3 ± 0.4 17.9 ± 0.6 16.8 ± 0.6 18.3 ± 0.8 16.8 ± 0.7 18.3 ± 0.9
NE% (%) 14.9 ± 5.8 12.5 ± 6.5 10.4 ± 3.1 13.7 ± 3.5 17.1 ± 4.8 17.5 ± 6.3
EO% (%) 0.9 ± 0.6 1.2 ± 0.9 0.2 ± 0.4* 0.7 ± 0.6 0.3 ± 0.3* 1.1 ± 0.6
BA% (%) 0.5 ± 0.6 0.5 ± 0.5 0.5 ± 0.4 0.8 ± 0.3 0.5 ± 0. 30.2 ± 0.3
MO% (%) 12.2 ± 4.2 12.5 ± 3.5 8.8 ± 2.4* 13.7 ± 3.0 11.5 ± 4.8 13.1 ± 6.3
LY% (%) 69.3 ± 7.9 71.9 ± 6.6 75.4 ± 5.3 67.9 ± 6.3 68.5 ± 4.8 66.2 ± 8.9
BALF Cell Counts
BC (104/ml) 39.4 ± 45.1 12.5 ± 10.0 27.1 ± 37.6 39.9 ± 18.1* 21.8 ± 13.1 28.4 ± 23.5
WBC% (%) 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0
  1. Each value represents mean ± standard deviation of 10 rats
  2. * Significantly different from control, p < 0.05