Diesel engine exhaust and lung cancer risks – evaluation of the meta-analysis by Vermeulen et al. 2014

Table 7 Silverman et al. [4]: Linear regression with fixed effects for log RR with weights proportional to the inverse of the respective variance

log RR	Coef.	Std. Err.	t	P	95 % CI
Dose	0.00121	0.00055	2.20	0.27 (0.028)	−0.00579 (0.00013	0.00821 0.00229)
Constant	−0.148	0.299	−0.49	0.71	−3.95	3.65
Crump et al. [14], REC4
Dose	0.00033	0.00051	0.64	0.63 (0.53)	−0.00615 (−0.00067	0.00680 0.00132)
Constant	0.00541	0.358	0.02	0.99	−4.54	4.55
Crump et al. [14], REC6
Dose	0.00021	0.00021	1.01	0.50 (0.31)	−0.00247 (−0.00020	0.00289 0.00063)
Constant	0.137	0.108	1.27	0.42	−1.23	1.51

Coefficient (Coef.) of the cumulative exposure (Dose) to DEE in μg/m³-years and absolute term (Constant) with standard deviation (Std.Err.); t-test statistic for the coefficient with the corresponding P-value and a 95 % confidence interval for the coefficient, 95 % CI. The figures in parentheses are the results when using the standard normal distribution. Silverman et al. [4] was evaluated as used by Vermeulen et al. [1], and in accordance with the re-analysis by Crump et al. [14] with adjustment for radon exposure (REC4, REC6, cf. Table 3)

ISSN: 1745-6673