Fig. 4
From: Fipronil induces lung inflammation in vivo and cell death in vitro
Toll-like receptor 9 expression in mice lungs. Lungs sections from control groups (a-b) have TLR9 staining (arrows) in alveolar septum (a) and bronchiolar epithelium (a inset). The staining is also seen in the septal cells (arrows) in lung sections from control mice (b). The oral treatment reduced TLR9 staining in lung sections (c-d) and the staining (arrows) was observed in occasional septal cells (c). Bronchiolar epithelium (B; d and insets) showed much reduced TLR9 staining compared to the controls. Lung sections from mice treated with intranasal fipronil (e-f) showed intense staining (arrows) in alveolar septum (e) and bronchiolar epithelium (f). Bar: 100 μm