Impact of shift work on the diurnal cortisol rhythm: a one-year longitudinal study in junior physicians

Table 4 Longitudinal associations between shift work at baseline and diurnal cortisol pattern over one-year period of follow-up (N = 70)

	Cortisol at waking	Cortisol at +4 h	Cortisol at + 8 h	Cortisol at + 16 h
Shift work: No	0	0	0	0
Shift work: Yes	2.02 (0.68, 3.36)**	0.30 (−0.28, 0.88)	− 0.01 (− 0.38, 0.36)	0.02 (− 0.26, 0.29)
	Cortisol slope		Total cortisol AUC
Shift work: No	0		0
Shift work: Yes	−0.10 (− 0.17, − 0.03)**		5.84 (1.36, 10.32)*

Mixed regression, β (95% CI), *p < 0.05, **p < 0.01
Adjustment for biological factors (age and gender), work factors (professional tenure and working hours), family factors (partnership and children), behavioral factors (smoking, risky alcohol use, physical activity, overweight and obesity) at baseline

ISSN: 1745-6673