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Table 5 Predictive factors of work ability perception at the enrolment

From: Quality of life and work functionality in severe asthma patients: the impact of biological therapies

Features

N

Beta

95% CI

P-value

Gender

30

   

 F

 

-

-

 

 M

 

0.95

-4.1, 6.0

0.705

Age

30

-0.29

-0.55, -0.03

0.033

Age at diagnosis

30

-0.02

-0.20, 0.17

0.845

BMI

30

0.22

-0.44, 0.88

0.504

Smoke

30

0.05

-3.4, 3.5

0.979

Education level

30

   

 A

 

-

-

 

 B

 

1.7

-3.3, 6.8

0.487

 C

 

7.4

1.9, 13

0.010

Atopy

30

0.14

-4.8, 5.0

0.954

Nasal polyposis

30

-2.0

-6.7, 2.7

0.396

Drug

30

   

 Benralizumab

 

-

-

 

 Dupilumab

 

1.3

-4.2, 6.8

0.635

 Mepolizumab

 

-1.3

-8.2, 5.5

0.693

Relapses in the previous 12 months

30

-0.57

-4.2, 3.0

0.747

ACT

30

0.31

-0.63, 1.3

0.502

Spirometric values (M ± SD)

 FEV1 (L)

30

3.8

-0.69, 8.2

0.094

 FEV1 (%)

30

0.22

0.04, 0.40

0.020

 FVC (L)

30

1.1

-1.4, 3.7

0.362

 FVC%

30

0.16

-0.05, 0.36

0.132

 FEV1/FVC

30

0.10

-0.13, 0.32

0.386

FeNO (ppb)

30

0.03

-0.35, 0.40

0.879

Eosinophils (n/μL)

30

0.01

0.00, 0.02

0.144

Eosinophils %

30

0.55

-0.30, 1.4

0.193

Current work duration (years)

30

-0.04

-0.24, 0.16

0.677

Type of contract

30

   

 Permanent

 

-

-

 

 Fixed-term

 

-3.4

-9.0, 2.1

0.212

 Freelance

 

2.2

-3.9, 8.3

0.468

Sector

30

   

 Private

 

-

-

 

 Public

 

-1.1

-6.2, 4.0

0.661

  1. Significant associations (p < 0.05) are shown in bold
  2. Abbreviations: A Primary level of education (primary and lower secondary school), B Secondary level of education (upper secondary school or vocational diploma), C Tertiary level of education (bachelor’s degree and postgraduate degree), BMI Body mass index, ACT Asthma Control Test, FEV1 Forced expiratory volume in the first second, FVC Forced vital capacity