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Challenges and opportunities for silicosis prevention and control: need for a national health program on silicosis in India

Abstract

Background

Silicosis has been one of the most serious occupational public health problems worldwide for many decades. The global burden of silicosis is largely unknown, although it is thought to be more prevalent in low and medium-income countries. Individual studies among workers exposed to silica dust in various industries, however, reveal a high prevalence of silicosis in India. This paper is an updated review of the novel challenges and opportunities for silicosis prevention and control in India.

Main body

The unregulated informal sector employs workers on contractual appointment thereby insulating the employers from legislative provisions. Due to a lack of awareness of the serious health risks and low-income levels, symptomatic workers tend to disregard the symptoms and continue working in dusty environments. To prevent any future dust exposure, the workers must be moved to an alternative job in the same factory where they will not be exposed to silica dust. Government regulatory bodies, on the other hand, must guarantee that factory owners relocate workers to another vocation as soon as they exhibit signs of silicosis. Technological advances such as artificial intelligence and machine learning might assist industries in implementing effective and cost-saving dust control measures. A surveillance system needs to be established for the early detection and tracking of all patients with silicosis. A pneumoconiosis elimination program encompassing health promotion, personal protection, diagnostic criteria, preventive measures, symptomatic management, prevention of silica dust exposure, treatment, and rehabilitation is felt important for wider adoption.

Conclusion

Silica dust exposure and its consequences are fully preventable, with the benefits of prevention considerably outweighing the benefits of treating patients with silicosis. A comprehensive national health program on silicosis within the public health system would strengthen surveillance, notification, and management of workers exposed to silica dust in India.

Background

Silicosis is an irreversible and fatal pneumoconiosis affecting millions of workers worldwide who are exposed to silica dust [1]. Mining, tunneling, quarrying, sculpturing, foundries, and manufacturing of building construction materials are some of the key industries in which workers are exposed to silica dust [2]. Although silicosis is considered to be more prevalent in low and middle-income countries, evidence on its global burden is limited, due mostly to underreporting and low detection due to a lack of surveillance [1, 3,4,5,6]. In 2019, an estimated 2.65 million cases of silicosis were reported worldwide [7]. Globally, in 2019, over 12.9 thousand deaths and 0.65 million disability-adjusted life years (DALYs) were attributed to silicosis, accounting for three-fourths of all pneumoconiosis DALYs [1, 7]. Many workers develop silicosis after 5–10 years of being exposed to silica dust and die within 15 years, undermining the seriousness of the disease [1]. The permissible exposure limit (PEL) for silica dust in Indian mines is set at 0.15 mg/m3, calculated as an 8-hour time-weighted average [8]. In contrast, the U.S. Occupational Safety and Health Administration (OSHA) prescribes a PEL of 0.05 mg/m3 and an action level of 0.025 mg/m3 [9]. Similarly, the American Conference of Government Industrial Hygienists (ACGIH) sets a threshold limit value of 0.025 mg/m3 [10]. These variations indicate that the prescribed limits for crystalline silica dust in India are significantly higher than the standards prescribed in Western countries, highlighting the need for a thorough review [11].

By mid-2023, with a population exceeding 1.43 billion individuals, India is poised to surpass all other nations and become the world’s most populous country, while also solidifying its position as the third most sought-after manufacturing destination globally [12, 13]. Furthermore, by 2025, it is projected that India will house approximately 25% of the global working population (~ 0.8 billion), a majority of whom, roughly 92%, will be engaged in the informal sector [14,15,16]. It is within this informal sector that the majority of occupations exposing workers to silica dust are found in India. In 2015-16, an estimated 11.5 million workers in India were employed in occupations associated with silica dust, a number expected to surge to 52 million by the year 2025-26 [14, 17]. Rajasthan’s mining sector is home to roughly 30,000 mines that reaps sandstone, marble, and granite [18]. These mines are spread across several districts of Rajasthan and employ nearly 3 million workers and another 3.2 million are employed in the construction industry [18, 19]. Around 50,000 workers are working in the agate industry in Khambhat, Gujarat [20]. According to recent estimates, the construction industry employs an approximate workforce of nearly 60 million workers in India [21].

Studies have reported varying prevalence rates of silicosis across different regions and occupations among workers exposed to silica dust in India (Table 1) [22,23,24,25,26,27,28]. In Haryana, the prevalence was found to be 9% among mine workers,[29] while in Rajasthan, it ranged from 37% among general mine workers to a higher 38–79% among stone mineworkers [18, 24, 25, 30,31,32]. The introduction of the pneumoconiosis policy in 2019 in Rajasthan led to the diagnosis of 23,436 cases of silicosis out of 192,143 persons screened, indicating a prevalence of 12% among stone carving and stone mining workers, which corresponds to the prevalence reported in sandstone quarries in Rajasthan [11, 19]. The investigators emphasized that their studies in Rajasthan revealed a higher prevalence of silicosis among stone carving workers compared to stone mining workers [6, 19]. In other regions, ordnance factory workers in Delhi had a prevalence of 3.5%,[33] while slate pencil workers in Madhya Pradesh exhibited rates ranging from 25 to 55% [34, 35]. Gujarat, known for its agate and pottery industries, recorded a prevalence varying from 18 to 69% among agate workers and 15% among pottery workers [26, 27, 36]. Silicosis prevalence among stone grinders in Gujarat was reported at 14–18% [37, 38]. Additionally, Mumbai’s flour mill workers had a prevalence rate of 30% [39]. Furthermore, the co-occurrence of silicosis and tuberculosis, referred to as silico-tuberculosis, was observed among mineworkers in Rajasthan at a rate of 7%,[24] while agate workers in Gujarat had a prevalence of 5%, and stone mineworkers as well as stone grinders in Gujarat and Rajasthan recorded rates of 12–25% [25, 37, 38, 40].

Table 1 Prevalence of silicosis and silico-tuberculosis in various occupations in India

Many challenges exist in the prevention and control of this ancient and preventable disease such as unregulated informal sector, diagnostic difficulties, absence of a surveillance mechanism, inadequate staff, and a lack of awareness [28, 41,42,43,44]. Apart from routine dust control measures, several initiatives may be undertaken to control silicosis, including raising awareness, building capacity, improving health systems to treat silicosis patients, integrating silicosis control with tuberculosis control, and strict adherence to statutory regulations [28, 41,42,43,44]. Along with the age-old challenges and solutions for silicosis prevention and control, this comprehensive review highlights several newer challenges and solutions.

Main text

Challenges

The prevention and control of silicosis in India face significant challenges, including worker-related, disease-related, and systemic challenges (Table 2). One major programmatic challenge is the absence of a comprehensive national health program dedicated to silicosis control, resulting in a lack of coordination among stakeholders and limited surveillance mechanisms.

Table 2 Challenges in the prevention and control of silicosis in India

Worker-related challenges

Job-related issues

People working in the silica-dust industries are mostly contract laborers, making it difficult for them to obtain new employment due to a lack of job opportunities [18, 41, 42, 45,46,47,48,49]. Workers fear that if they are diagnosed with any silica dust-related illnesses, they may be asked to quit, thereby exposing them to unemployment [45, 46]. They do not seek healthcare on time and instead return to dusty work conditions out of fear of getting laid off [42, 44, 46]. Due to the low socioeconomic conditions, vocational rehabilitation of people working in silica dust-related occupations into different occupations is challenging [20]. Moreover, employers do not allow them to take time off to visit the hospital, and workers prefer to consult unqualified doctors in the event of any health-related complaints to avoid wage loss [45, 50].

Lack of awareness

Due to a lack of awareness, patients do not suspect a major health problem and believe that silicosis cannot affect them [18, 42, 51,52,53,54,55]. Due to a lack of awareness, coupled with lower education levels that contribute to it, workers in these occupations not only fail to seek appropriate healthcare guidance,[37, 42] but also exhibit a limited inclination towards using personal protective equipment [49, 51,52,53,54, 56].

Disease-related challenges

Silicosis is frequently misdiagnosed as TB [6, 28, 42, 44, 45]. Because the symptoms of tuberculosis (TB) and silicosis are similar, factory workers too believe that they have recurrent TB [18]. As silicosis is incurable, patients’ symptoms continue even after the completion of TB treatment. Upon symptomatic relief, workers return to dusty work settings, increasing their exposure to silica dust even more. The vicious cycle continues, and they experience the progression of silicosis and relapses of TB [40].

Silica dust clogs the alveoli of the lungs,[57] leading to the potentially fatal complication pneumothorax among patients with chronic silicosis [58]. Dormant TB bacilli are occasionally triggered in individuals with silicosis due to macrophage dysfunction and immunological dysregulation, resulting in TB relapses [59, 60]. Because fibrosis of the lung tissue reduces blood flow, TB medications are unable to permeate the tissue and hence reach lower concentrations [59, 61, 62]. Although non-pathogenic, patients with silicosis often demonstrate the presence of non-tuberculous mycobacteria along with the TB bacilli [63,64,65]. Non-tuberculous mycobacteria are resistant to several of the medications included in the national TB treatment regimen [66].

Systemic challenges

Control measures aimed at mitigating exposure have generally been implemented and enhanced over time in developed countries like North America and Europe [67]. However, the situation contrasts in developing nations such as China and India, where high levels of exposure persist, leading to a higher prevalence of silicosis [67]. Notable progress has been made in addressing the issue of silicosis in specific occupational settings, such as sandblasting of jeans, with countries like the United States and Germany implementing positive measures like independent factory inspections in response to documented studies [68]. However, it is worth noting that the extent of similar actions being taken in India appears to be limited, highlighting the need for further attention and initiatives in this regard.

The majority of silicosis cases are anticipated to be reported in smaller units and cottage industries [28, 41]. Small enterprises may also be exempt from the statutory norms outlined in the Factories Act, 1948, and the Mines Act, 1952 [20, 28, 41, 44]. As a result, accountability must be assigned among the statutory bodies to execute the provisions of the Factories Act, 1948, the Mines Act, 1952, and the Building and Other Construction Workers (BOCW) Act, 1996, at the smaller units [40]. According to Sect. 112 of the Factories Act, 1948, the Chief Inspector of Factories in each respective state possesses the authority to designate any hazardous unit, regardless of the number of workers employed, as subject to the legal provisions and regulations stated in the Act [69]. As of now, only a limited number of states, such as Gujarat, have taken the initiative to pass resolutions affirming the application of these provisions within their jurisdictions.

Silicosis, recognized as a notifiable and compensable disease under the Factories Act, 1948, and the Mines Act, 1952, remains severely underdiagnosed and underreported in India, as evidenced by the recent annual report of the Ministry of Labour and Employment [69,70,71]. The report revealed a mere 441 cases of silicosis reported between 2008 and 2022, underscoring the significant extent of underdiagnosis and underreporting within the country [71]. This discrepancy can be attributed to employers’ inclination to withhold notifications from their factories to avoid legal complications and the subsequent obligation to provide compensation to affected employees [20, 41, 44, 72]. There are also challenges surrounding the intention and integrity of the implementing agencies as far as the unorganized sector is concerned [20, 42, 44]. Additionally, there are concerns regarding the outsourcing of medical examinations of workers to doctors who do not understand occupational health [40].

Employers do not allow time for workers to consult a doctor or visit a health facility if they become unwell [42]. Employers also fail to rehabilitate patients and neglect their relocation to less hazardous environments [41, 42]. Concerns have been raised over the scarcity of water for wet drilling in mines and the subsequent decline in drilling efficiency,[44] highlighting the tendency of employers to prioritize the speed of work completion over worker safety. Implementing dust control measures proves costly for industries [44].

In India, the Factories Act of 1948 and the Mines Act of 1952 stipulate the mandatory periodic measurement of dust and silica concentrations in workplaces [69, 70]. However, employers in the country exhibit a lack of awareness regarding these requirements, and the associated measurement processes are perceived as costly. Consequently, many employers in the industrial sector refrain from conducting such measurements and consequently fail to provide relevant data. Furthermore, those employers who are interested in implementing dust measurements often lack knowledge of suitable methods, equipment, and expertise. Additionally, there is a notable absence of public or private agencies that offer support for conducting dust measurements. To address these challenges, the government can play a pivotal role by acting as a facilitator and providing necessary support to enable the implementation of dust measurements in workplaces.

The current state of awareness and clinical suspicion for silicosis among medical officers and clinicians appears to be inadequate, as they exhibit limited knowledge and understanding of several aspects, even after diagnosing a patient with silicosis [44]. Insufficient attention is given to obtaining the occupational history of patients during medical consultations. Consequently, the misdiagnosis and underreporting of silicosis cases are prevalent. The necessity of enhancing the diagnostic skills of doctors in India, specifically in the interpretation of International Labour Organization (ILO) radiographs for the detection of silicosis is emphasized [44].

In India, a standardized diagnostic algorithm and guidelines for silicosis certification are lacking, as is clarification on who may certify a patient as suffering from silicosis [41, 42, 44]. An exception is the western Indian state of Rajasthan, where there is a policy on the detection, prevention, relief, and rehabilitation of pneumoconiosis [6, 73]. However, there are multiple challenges in its implementation, including unawareness, misdiagnosis, and low reporting rates [44]. In the absence of a surveillance mechanism for silicosis, data is not being captured, and the true burden remains elusive [41]. In the absence of a national health program, there is a lack of coordination among various stakeholders involved in silicosis control [44].

Opportunities

In light of the underreporting of silicosis cases, the actual burden of the disease remains unknown, underscoring the urgent need to enhance diagnostic facilities, provide training to medical officers at primary healthcare centers for accurate diagnosis of silicosis, and establish a robust surveillance mechanism (Table 3). A routine surveillance system would not only generate comprehensive data on the true prevalence of silicosis but also enable monitoring of the disease’s incidence, identification of high-risk areas, and analysis of associated risk factors. By providing timely and reliable information, such a system of surveillance would enable public health authorities to effectively adopt targeted preventive measures and interventions to limit the impact of silicosis.

Table 3 Opportunities for prevention and control of silicosis in India

Surveillance

Identifying and mapping locations in India where industries generating silica dust are situated would be the first step toward eliminating the disease [22, 41]. To facilitate effective monitoring, it is essential to define priority districts and sub-district areas/clusters [22, 41]. Considering that a significant portion of these factories operates in the informal sector, tracking efforts would help concentrate control activities specifically on these areas, ensuring targeted implementation of preventive and control measures.

A surveillance system needs to be established for the early detection and tracking of all patients with silicosis [2, 6, 28, 74, 75]. Organizing diagnostic camps in industries where silica dust is generated would also aid in the early detection of silicosis. It is suggested that active case finding, which is currently a part of the national TB program, be expanded to include silicosis [40, 44]. It is a statutory requirement to conduct periodic medical examinations of workers exposed to silica dust every six months [6, 22, 27, 69, 70, 75, 76]. Considering the high prevalence of TB among silica dust-exposed individuals, TB surveillance should be a part of periodic medical examinations [27].

Preventing silica dust exposure

Silica dust reduction

Several studies conducted in India have consistently reported silica dust levels exceeding the prescribed limits set by various agencies, ranging from 0.025 to 0.15 mg/m3 [11, 77]. Additionally, lower but still significant levels have been identified, emphasizing the importance of minimizing occupational exposure to mitigate the risk of silicosis [78]. Within specified mining sectors, such as limestone (0.015 mg/m3), iron (0.012 mg/m3), and bauxite (0.008 mg/m3) mines, crystalline silica concentrations were found to be below the prescribed permissible exposure limit (PEL) of 0.15 mg/m3 for Indian mines [78]. Conversely, in sandstone mines, concentrations were slightly above the PEL (0.17 mg/m3) and in granite and masonry mines, they were lower than the PEL (0.12 mg/m3) [77]. Nevertheless, researchers suggest the need for a lower PEL in India, as even at mean levels of 0.12 mg/m3, cases of silicosis were reported among workers [11]. Notably, stone crushing sites (0.098–2.29 mg/m3), coal mines (2.7–5.3 mg/m3), and agate workers (0.11–0.12 mg/m3) exhibited silica dust concentrations well above the limits established by ACGIH and OSHA, which range from 0.025 to 0.05 mg/m3 [36, 79,80,81,82]. Moreover, other studies documented significantly high levels of silica dust concentrations among slate pencil workers (55–57%), quartz manufacturers (26%), and stone crushers (19%) [34, 83, 84]. Among stone mine workers with TB, silica dust concentrations ranged between 0.11 and 0.16 mg/m3, further emphasizing the critical need to reduce occupational exposure to silica dust in order to mitigate the prevalence of TB [85].

Currently, various preventive measures are in place to reduce silica dust, including the use of ventilation systems, water suppression techniques, dust control equipment, and personal protective equipment such as masks. Exhaust systems should be implemented in factories where silica dust is generated [2, 22, 48, 55, 75, 86,87,88,89]. Dust control measures have been recognized as an effective engineering control measure for reducing worker exposure to silica dust [48, 86, 88]. Installing exhaust fans in factories where silica dust is generated might also be beneficial [2]. It is critical to make such systems cost-effective, as high operational costs are a deterrent to using such exhaust systems [43, 44, 86, 90, 91]. Many factories/cottage industries use a water spraying technique, often known as a wet process [2, 20, 22, 42, 82, 87,88,89, 92, 93]. A constant flow of water droplets is placed over the spot where the stones are polished. Alternatively, in mines, some drilling equipment only operates when water is supplied to them. Places, where the silica dust is generated in factories, should be enclosed so that only a small number of workers are exposed to it. In addition, only a restricted number of workers should be permitted in sections of the factory where dust is formed. Technological advances such as artificial intelligence and machine learning might help industries implement effective and cost-efficient dust control measures [94, 95]. While technological solutions for dust control are readily available, the lack of enforcement mechanisms and the attitude of both employers and employees towards implementing these measures pose significant obstacles to their effective adoption.

Silica dust alternatives

Alternative uses for silica dust generated in the industry should be investigated. The generated dust can be utilized as fillers in the manufacturing of concrete and construction materials [96]. Because of the water spraying mechanism, silica dust is settling on the ground as wet dust. However, as the wet dust dries, it becomes dry silica dust. As a result, wet dust should be disposed of using a deep burial technique. Employers should be offered subsidies to help them set up silica dust disposal systems. Alternatively, a more hazardous material (for example, stones) should be substituted with a less hazardous material.

Prevention activities

In the absence of effective treatments, widespread preventative activities are recommended for silicosis [75]. A part of the total budget allocated by the government for rehabilitative activities should be targeted for preventive efforts. An industrial estate should be created near the houses of employees in cottage industries so that all workers may work together [48, 97]. Because all workers would be in one location, the procedure of registering workers and undertaking preventative activities and periodic medical checks would be streamlined [48]. The state government of Gujarat had planned to relocate cottage industries of agate workers from Khambhat city to an alternative location, offering land and necessary infrastructure [48]. Additionally, a cooperative society was proposed to address environmental and occupational health concerns, with the owners taking responsibility [48]. However, the implementation of this plan has been delayed due to potential challenges related to land allotment and monitoring.

Integrating Basic Occupational Health Services (BOHS) with primary health care can provide an effective approach to the prevention and control of silicosis [98]. The integration of BOHS with primary health care can ensure that workers are regularly screened for early detection of silicosis, and appropriate treatment is provided [98]. This can also ensure that the community is aware of the health risks associated with exposure to silica dust and the preventive measures to reduce exposure [98]. Additionally, to tackle the problem of silicosis, coordination is essential across multiple stakeholders such as health, labor and employment, and pollution control boards [22, 42, 76]. In India, the district collector (administrative head of a district) should promote such collaboration among several departments for silicosis prevention and control.

Employer’s role

To prevent any future dust exposure, the workers must be moved to alternative job options within the same factory that offers reduced or no exposure to silica dust, considering factors such as factory layout, job-specific hazards, and other relevant factors that could influence exposure levels. Implementing job-shifting practices can present practical challenges that need to be carefully addressed. Government regulatory bodies, on the other hand, must guarantee that factory owners relocate workers to another vocation as soon as they exhibit signs of silicosis. It is critical not to dismiss the individual from his employment, since this would result in further malnutrition and the spread of other diseases. As a result, such a work transition should ensure that their source of income stays intact.

Reduction of dust at the source through elimination, substitution, engineering control, administrative control, and lastly the use of personal protective equipment is recommended [2, 74, 88, 99, 100]. It is reiterated that this should be the factory’s hierarchy of control measures employed for dust control [100]. Industrial hygiene procedures are critical for reducing silica dust at the source and in its journey in the air before it reaches the worker. Personal protection equipment such as masks, goggles, hand gloves, and respirators are recommended for decreasing worker exposure to silica dust [2, 22, 88, 99].

Effective law enforcement

It is vital to post qualified personnel in implementing agencies to execute the provisions of various legislative Acts [42]. The certifying surgeons assigned to the implementing agencies are merely MBBS doctors with limited understanding, expertise, or credentials in occupational health [42, 44]. Courses such as the Associate Fellow in Industrial Health (AFIH), offered by several institutes under the supervision of the Ministry of Labor and Employment, educate medical officers on various aspects of occupational health. Larger portions of occupational health must be incorporated into the MBBS curriculum so that medical officers have an understanding before beginning their profession or being recruited [22, 28, 41, 42, 74,75,76]. A short course in integrity and ethics might improve their service delivery at work. Furthermore, it is imperative to augment the workforce in the relevant departments of the Ministry of Labour and Employment (Government of India) to ensure an adequate number of personnel available for conducting regular visits to industries and effectively monitoring compliance with safety measures [20].

Programmatic guidelines

Standardized guidelines on diagnosis, symptomatic therapy, comorbidity management, and palliative care should be developed and circulated widely. Rehabilitation mechanisms such as physiotherapy, oxygen therapy, and other alternative therapies should be a part of the standardized document. Considering that health is under the purview of individual states in India, it is advisable for other states, following the example of Rajasthan, to consider implementing a monetary compensation policy for individuals affected by silicosis [6, 28, 73]. The pneumoconiosis policy in Rajasthan was established after a decade of concerted efforts and representations by various government organizations, including the Rajasthan State Human Rights Commission and the Association for Rural Advancement through Voluntary Action and Local Involvement (ARAVALI, https://aravali.org.in/publicationsresearch.html), as well as non-governmental organizations like the Mine Labour Protection Campaign (https://minelabour.org/) [6, 22, 73, 101]. These entities brought attention to the high prevalence of silicosis among stone mine workers in the state and emphasized the necessity for financial rehabilitation. Factors such as a higher prevalence of silicosis cases, increased awareness of the issue, and proactive efforts by local authorities contributed to the adoption of these policies. While the prevalence of silicosis may vary across different states in India, the decision to implement proactive measures depends on factors such as political will and resource availability. Therefore, it is essential to encourage other states to follow Rajasthan’s example and take decisive steps towards mitigating the burden of silicosis in their respective regions.

A pneumoconiosis elimination program encompassing health promotion, personal protection, diagnostic criteria, preventive measures, symptomatic management, prevention of silica dust exposure, treatment, and rehabilitation is felt important for wider adoption [28]. A distinct ‘National Silicosis Control Program’ with reporting and review/monitoring, would result in program activities being funded under a separate budget head [25, 28, 41]. Until such a program is established, silicosis control activities should be integrated with TB elimination efforts [22, 28, 40, 48, 76].

Conclusions

Silicosis continues to be a fatal occupational disease, with serious consequences on workers’ productivity and quality of life. Silicosis is not a state-specific issue in India; it is a national one. Silica dust exposure and its consequences are fully preventable, with the benefits of prevention considerably outweighing the benefits of treating patients with silicosis. Data from periodic medical examinations of workers in silica-dust-producing industries should be analyzed to generate robust evidence that can support and direct targeted interventions aimed at mitigating the risks associated with silica dust exposure. Not only should employees and employers be educated about the fatal disease, but also doctors, including interns and rural medical officers, need to be well-informed. Preventing worker exposure to silica dust will have significant financial implications (e.g., through improved worker productivity, reduced healthcare costs, and minimized loss of workdays) and provide an impetus to India’s untapped potential - a healthy labor force. With India being the third-most sought-after manufacturing destination globally, a comprehensive national health program on silicosis would be a necessary intervention to protect workers’ health.

Data Availability

There was no primary or secondary data collected for this review article.

Abbreviations

AFIH:

Associate Fellow in Industrial Health

BOCW:

Building and Other Construction Workers

DALY:

Disability Adjusted Life Years

MBBS:

Bachelor in Medicine and Bachelor in Surgery

TB:

Tuberculosis

References

  1. Chen S, Liu M, Xie F, Global. and national burden and trends of mortality and disability-adjusted life years for silicosis, from 1990 to 2019: results from the Global Burden of Disease study 2019. BMC Pulm Med [Internet]. 2022;22:1–10. Available from: https://doi.org/10.1186/s12890-022-02040-9.

  2. Leung CC, Yu ITS, Chen W. Silicosis Lancet. 2012;379:2008–18.

    Article  CAS  PubMed  Google Scholar 

  3. Alaguney ME, Yildiz AN, Demir AU, Ergor OA. Physicians’ opinions about the causes of underreporting of occupational diseases. Arch Environ Occup Health [Internet]. 2020;75:165–76. Available from: https://www.tandfonline.com/doi/full/https://doi.org/10.1080/19338244.2019.1594663.

  4. Patel J. Difficulties of recording and notification of accidents and diseases in developing countries [Internet]. Int. Labour Organ. International Labour Organization; 2019 [cited 2022 Sep 28]. Available from: https://www.ilo.org/global/topics/safety-and-health-at-work/events-training/events-meetings/world-day-for-safety/33thinkpieces/WCMS_680366/lang--en/index.htm.

  5. Moreno-Torres LA, Ventura‐Alfaro CE. Underreporting trends of occupational illnesses in Mexico. J Occup Health. 2018;60:85–8.

    Article  PubMed  Google Scholar 

  6. Sishodiya PK. Silicosis-An ancient disease: providing succour to silicosis victims, lessons from Rajasthan model. Indian J Occup Environ Med. 2022;26:57–61.

    PubMed  PubMed Central  Google Scholar 

  7. Institute for Health Metrics and Evaluation. Global Health Metrics: Silicosis — Level 4 cause [Internet]. 2019. Available from: https://www.healthdata.org/sites/default/files/disease_and_injury/gbd_2019/topic_pdf/cause/511.pdf.

  8. Directorate General of Mines Safety (Ministry of Labour and Employment). The metalliferous mines regulations, 1961 [Internet]. Government of India. ; 1960. Available from: https://www.dgms.gov.in/writereaddata/UploadFile/Metalliferous Mines Regulation, 1961.pdf.

  9. Occupational Safety and Health Administration (United States Department of Labour). Respirable crystalline silica (standard number 1910.1053) [Internet]. [cited 2023 May 9]. Available from: https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.1053.

  10. American Conference of Government Industrial Hygienists (ACGIH). SILICA, CRYSTALLINE — α-QUARTZ AND CRISTOBALITE [Internet]. [cited 2023 May 9]. Available from: https://www.acgih.org/silica-crystalline-a-quartz-and-cristobalite/.

  11. Dhatrak S, Nandi S. Assessment of silica dust exposure profile in relation to prevalence of silicosis among indian sandstone mine workers: need for review of standards. Am J Ind Med. 2019;63:277–81.

    Article  PubMed  Google Scholar 

  12. United Nations Population Fund. State of World Population report 2023 [Internet]. United Nations Population Fund. ; 2023. Available from: https://www.unfpa.org/sites/default/files/swop23/SWOP2023-ENGLISH-230329-web.pdf.

  13. India Brand Equity Foundation - an initiative of the Ministry of Commerce and Industry (Government of India). Manufacturing Sector in India: Market Size, FDI, Govt Initiatives [Internet]. 2023 [cited 2023 May 11]. Available from: https://www.ibef.org/industry/manufacturing-sector-india.

  14. TeamLease. India labour report 2009 [Internet]. 2009. Available from: https://www.teamleasegroup.com/sites/default/files/resources/teamlease_labourreport2009.pdf.

  15. International Labour Organization (ILO). World employment and social outlook: Trends 2020 [Internet]. 2020. Available from: https://www.ilo.org/wcmsp5/groups/public/---dgreports/---dcomm/---publ/documents/publication/wcms_734479.pdf.

  16. International Labour Organization. Decent Work Country Programme for India (2018–2022) [Internet]. New Delhi: ILO Decent Work Team for South Asia and Country Office for India. ; 2018. Available from: https://www.ilo.org/wcmsp5/groups/public/---asia/---ro-bangkok/---sro-new_delhi/documents/publication/wcms_650119.pdf.

  17. Rees D, Murray J. Silica. In: Newman TA, Cullinan P, Blanc P, Pickering A, editors. Park Occup Lung Disord. 4th ed. Boca Raton: CRC Press; 2016. pp. 187–205.

    Google Scholar 

  18. Sharma DC. Miners fight for breath in indian state. Lancet Respir Med. 2015;3:181.

    Article  CAS  PubMed  Google Scholar 

  19. Sishodiya PK. SP-02 Prevalence of silicosis in stone carving and sandstone mining industry in Rajasthan. Occup Environ Med [Internet]. BMJ Publishing Group Ltd; 2023. p. A3.1-A3. Available from: https://oem.bmj.com/content/80/Suppl_1/A3.1.

  20. Patel J, Robbins M. The agate industry and silicosis in Khambhat, India. New Solut. 2011;21:117–39.

    Article  PubMed  Google Scholar 

  21. Chand R, Singh J. Workforce changes and employment: some findings from PLFS data series [Internet]. NITI Aayog Discuss. Pap. New Delhi: Government of India; 2022. Available from: https://www.niti.gov.in/sites/default/files/2022-04/Discussion_Paper_on_Workforce_05042022.pdf.

  22. Rajasthan State Human Rights Commission. Special report on silicosis [Internet]. Rajasthan, India. ; 2014. Available from: https://rshrc.rajasthan.gov.in/writereaddata/Judgements/202208250221108626755Special_Report_Silicosis.pdf.

  23. Dhooria S, Sehgal IS, Agarwal R. Silica-associated lung disease in developing countries. Curr Opin Pulm Med [Internet]. 2023;29:65–75. Available from: https://journals.lww.com/https://doi.org/10.1097/MCP.0000000000000940.

  24. Rajavel S, Raghav P, Gupta MK, Muralidhar V. Silico-tuberculosis, silicosis and other respiratory morbidities among sandstone mine workers in Rajasthan- a cross-sectional study. Dahms H-U, editor. PLoS One [Internet]. 2020 [cited 2022 Dec 13];15:e0230574. Available from: https://doi.org/10.1371/journal.pone.0230574.g001.

  25. Nandi SS, Dhatrak SV, Sarkar K. Silicosis, progressive massive fibrosis and silico-tuberculosis among workers with occupational exposure to silica dusts in sandstone mines of Rajasthan state: an urgent need for initiating national silicosis control programme in India. J Fam Med Prim Care. 2021;10:686.

    Article  Google Scholar 

  26. Chaudhury N, Phatak A, Paliwal R, Raichaudhari C. Silicosis among agate workers at Shakarpur: an analysis of clinic-based data. Lung India. 2010;27:221–4.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Saiyed HN, Ghodasara NB, Sathwara NG, Patel GC, Parikh DJ, Kashyap SK. Dustiness, silicosis & tuberculosis in small scale pottery workers. Indian J Med Res [Internet]. 1995;102:138–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8543354.

  28. Sharma N, Kundu D, Dhaked S, Das A. Silicosis and silicotuberculosis in India. Bull World Health Organ [Internet]. 2016;94:777–8. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043201/pdf/BLT.15.163550.pdf/.

  29. Govindagoudar MB, Singh PK, Chaudhry D, Chaudhary R, Sachdeva A, Dhankhar S et al. Burden of Silicosis among stone crushing workers in India. Occup Med (Chic Ill) [Internet]. 2022;72:366–71. Available from: https://academic.oup.com/occmed/article/72/6/366/6420087.

  30. Sishodiya PK, Nandi SS, Dhatrak SV. Detection of silicosis among stone mine workers from Dholpur district [Internet]. Nagpur, India: National Institute of Miner’s Health; 2014. Available from: http://www.indianet.nl/pdf/DetectionOfSilicosisAmongStoneMineWorkersFromDholpurDistrict.pdf.

  31. Sishodiya PK, Nandi SS, Dhatrak SV. Detection of silicosis among stone mine workers from Karauli district : Report - II [Internet]. Nagpur, India: National Institute of Miner’s Health; 2014. Available from: http://www.indianet.nl/pdf/DetectionOfSilicosisAmongStoneMineWorkersFromKarauliDistrict-Report-II.pdf.

  32. Sishodiya PK, Nandi SS, Dhatrak SV. Detection of silicosis among stone mine workers from Karauli district [Internet]. Nagpur, India: National Institute of Miner’s Health; 2011. Available from: https://aravali.org.in/detection3.pdf.

  33. Viswanathan R, Boparai MS, Jain SK, Dash MS. Pneumoconiosis Survey of Workers in India Ordnance factory in India. Arch Environ Heal An Int J [Internet]. 1972;25:198–204. Available from: http://www.tandfonline.com/doi/abs/https://doi.org/10.1080/00039896.1972.10666161.

  34. Saiyed HN, Parikh DJ, Ghodasara NB, Sharma YK, Patel GC, Chatterjee SK, et al. Silicosis in slate pencil workers: I. An environmental and medical study. Am J Ind Med. 1985;8:127–33.

    Article  CAS  PubMed  Google Scholar 

  35. Jain SM, Sepaho GC, Khare KC, Dubey VS. Silicosis in Slate Pencil Workers. Chest [Internet]. 1977;71:423–6. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0012369216404095.

  36. Rastogi SK, Gupta BN, Chandra H, Mathur N, Mahendra PN, Husain T. A study of the prevalence of respiratory morbidity among agate workers. Int Arch Occup Environ Health [Internet]. 1991;63:21–6. Available from: http://link.springer.com/https://doi.org/10.1007/BF00406193.

  37. Tiwari RR, Sharma YK. Respiratory Health of Female Stone Grinders with Free Silica Dust Exposure in Gujarat, India. Int J Occup Environ Health [Internet]. 2008;14:280–2. Available from: http://www.tandfonline.com/doi/full/https://doi.org/10.1179/oeh.2008.14.4.280.

  38. Tiwari R, Narain R, Sharma Y, Kumar S. Comparison of respiratory morbidity between present and ex-workers of quartz crushing units: Healthy workers′ effect. Indian J Occup Environ Med [Internet]. 2010;14:87. Available from: http://www.ijoem.com/text.asp?2010/14/3/87/75695.

  39. Athavale A, Iyer A, Sahoo D, Salgia K, Raut A, Kanodra N. Incidence of silicosis in flourmill workers. Indian J Occup Environ Med. 2011;15:104–8.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Rupani MP. A mixed-methods study on impact of silicosis on tuberculosis treatment outcomes and need for TB-silicosis collaborative activities in India. Sci Rep [Internet]. 2023;13:2785. Available from: https://www.nature.com/articles/s41598-023-30012-4.

  41. Kulkarni G. Prevention and control of silicosis: A national challenge. Indian J Occup Environ Med [Internet]. 2007;11:95. Available from: http://www.ijoem.com/text.asp?2007/11/3/95/38456.

  42. Shamim M, Saraf A. Examining Legal and Policy Provisions on Silicosis in the Context of Sandstone Mining in Karauli, Rajasthan-India. Indian J Public Heal Res Dev [Internet]. 2017;8:407. Available from: http://www.indianjournals.com/ijor.aspx?target=ijor:ijphrd&volume=8&issue=4&article=078.

  43. Jindal SK. Silicosis in India: past and present. Curr Opin Pulm Med. 2013;19:163–8.

    Article  CAS  PubMed  Google Scholar 

  44. Chaturvedi O, Mantri N, Joshi NK, Goel AD, Jain YK, Gupta MK et al. Challenges in the Implementation of the Rajasthan Pneumoconiosis Policy. Ann Work Expo Heal [Internet]. 2022;66:1162–72. Available from: https://academic.oup.com/annweh/article/66/9/1162/6694283.

  45. Mohammad S. Rehabilitation of silicosis victims of district Karauli, Rajasthan, India. Indian J Community Med [Internet]. 2019;44:347. Available from: http://www.ijcm.org.in/text.asp?2019/44/4/347/270815.

  46. Tiwary G, Gangopadhyay P. A review on the occupational health and social security of unorganized workers in the construction industry. Indian J Occup Environ Med [Internet]. 2011;15:18. Available from: http://www.ijoem.com/text.asp?2011/15/1/18/83003.

  47. Ahmad A. Socio-economic and health status of sandstone miners: a case study of Sorya village, Karauli, Rajasthan. Int J Res Med Sci. 2015;3:1159.

    Article  Google Scholar 

  48. Saiyed HN. Silicosis among children in the agate industry. In: Pronczuk-Garbino J, editor. Chidren’s Heal Environ a Glob Perspect [Internet]. Geneva: World Health Organization; 2005. Available from: https://apps.who.int/iris/bitstream/handle/10665/43162/9241562927_eng.pdf.

  49. Sharma DS, Patel TA. Study on work related factors of agate grinders in Shakarpura-Khambhat, Gujarat. Natl J Community Med [Internet]. 2011;2:60–3. Available from: http://www.njcmindia.org/home/view/88/.

  50. Ahmad A. Health-Seeking Behavior and Its Determinants among Mine Workers in the Karauli District of Rajasthan in India. Dubai Med J [Internet]. 2019 [cited 2022 Dec 13];2:7–16. Available from: https://www.karger.com/Article/FullText/500495.

  51. Yadav SP, Anand PK, Singh H. Awareness and Practices about Silicosis among the Sandstone Quarry Workers in Desert Ecology of Jodhpur, Rajasthan, India. J Hum Ecol [Internet]. 2011;33:191–6. Available from: https://www.tandfonline.com/doi/full/https://doi.org/10.1080/09709274.2011.11906359.

  52. Nandi S, Burnase N, Barapatre A, Gulhane P, Dhatrak S. Assessment of silicosis awareness among stone mine workers of Rajasthan state. Indian J Occup Environ Med [Internet]. 2018;22:97. Available from: http://www.ijoem.com/text.asp?2018/22/2/97/242545.

  53. Aggarwal BD. Worker Education Level is a Factor in Self-compliance with Dust-preventive Methods among Small-scale Agate Industrial Workers. J Occup Health [Internet]. 2013 [cited 2022 Dec 14];55:312–7. Available from: https://onlinelibrary.wiley.com/doi/full/https://doi.org/10.1539/joh.12-0167-OA.

  54. Falk L, Bozek P, Ceolin L, Levitsky M, Malik O, Patel J, et al. Reducing agate dust exposure in Khambhat, India: protective practices, barriers, and opportunities. J Occup Health. 2019;61:442–52.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  55. Sadhu H, Parikh D, Sharma Y, HN S, Rao P, Kulkarni P, et al. A follow up study of health status of small-scale agate industry workers. Indian J Ind Med. 1995;41:101–5.

    Google Scholar 

  56. Ahmad A. Awareness of workplace hazards and preventive measures among sandstone mineworkers in Rajasthan, India: a cross-sectional study. J Heal Soc Sci. 2017;2:69–82.

    Google Scholar 

  57. Fubini B, Hubbard A. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med [Internet]. 2003 [cited 2022 Nov 21];34:1507–16. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0891584903001497.

  58. Bairwa M, Joshi N, Agnihotri S. Silicosis with bilateral spontaneous pneumothorax in Rajasthan. Indian J Occup Environ Med [Internet]. 2019 [cited 2022 Dec 15];23:112. Available from: http://www.ijoem.com/text.asp?2019/23/3/112/273035.

  59. Allison AC, Harington JS, Birbeck M. An examination of the cytotoxic effects of silica on macrophages. J Exp Med [Internet]. 1966;124:141–54. Available from: https://rupress.org/jem/article/124/2/141/3986/AN-EXAMINATION-OF-THE-CYTOTOXIC-EFFECTS-OF-SILICA.

  60. Yew WW, Leung CC, Chang KC, Zhang Y, Chan DP. Can treatment outcomes of latent TB infection and TB in silicosis be improved? J Thorac Dis [Internet]. 2019;11:E8–10. Available from: http://jtd.amegroups.com/article/view/26382/19853.

  61. Lowrie DB. What goes wrong with the macrophage in silicosis? Eur J Respir Dis [Internet]. 1982;63:180–2. Available from: http://www.ncbi.nlm.nih.gov/pubmed/6284536.

  62. Snider DEJ. The relationship between tuberculosis and silicosis. Am Rev Respir Dis. 1978;118:455–60.

    PubMed  Google Scholar 

  63. Sonnenberg P, Murray J, Glynn J, Glyn Thomas R, Godfrey-Faussett P, Shearer S. Risk factors for pulmonary disease due to culture-positive M. tuberculosis or nontuberculous mycobacteria in South African gold miners. Eur Respir J [Internet]. 2000 [cited 2022 Dec 15];15:291. Available from: http://erj.ersjournals.com/content/15/2/291.

  64. Corbett EL, Hay M, Churchyard GJ, Herselman P, Clayton T, Williams BG, et al. Mycobacterium kansasii and M. scrofulaceum isolates from HIV-negative south african gold miners: incidence, clinical significance and radiology. Int J Tuberc Lung Dis. 1999;3:501–7.

    CAS  PubMed  Google Scholar 

  65. Blanco Pérez JJ, Pérez González A, Morano Amado LE, Guerra Vales JL, Vázquez Gallardo R, Salgado Barreira Á et al. Clinical Significance of Environmental Mycobacteria Isolated From Respiratory Specimens of Patients With and Without Silicosis. Arch Bronconeumol [Internet]. 2016 [cited 2022 Dec 15];52:145–50. Available from: https://www.archbronconeumol.org/en-clinical-significance-environmental-mycobacteria-isolated-articulo-S1579212916000082.

  66. Akrami S, Dokht khosravi A, Hashemzadeh M. Drug resistance profiles and related gene mutations in slow-growing non-tuberculous mycobacteria isolated in regional tuberculosis reference laboratories of Iran: a three year cross-sectional study. Pathog Glob Health [Internet]. 2022;1–11. Available from: https://www.tandfonline.com/doi/full/https://doi.org/10.1080/20477724.2022.2049029.

  67. Verma DK, Purdham JT, Roels HA. Translating evidence about occupational conditions into strategies for prevention. Occup Environ Med [Internet]. 2002;59:205–14. Available from: https://oem.bmj.com/lookup/doi/https://doi.org/10.1136/oem.59.3.205.

  68. Hobson J. To die for? The health and safety of fast fashion. Occup Med (Chic Ill) [Internet]. 2013;63:317–9. Available from: https://academic.oup.com/occmed/article-lookup/doi/https://doi.org/10.1093/occmed/kqt079.

  69. India. - The Factories Act, 1948 [Internet]. India; Available from: https://www.ilo.org/dyn/natlex/docs/WEBTEXT/32063/64873/E87IND01.htm.

  70. The Mines Act., 1952 [Internet]. India; Available from: https://www.dgms.gov.in/writereaddata/UploadFile/Mines Act, 1952.pdf.

  71. Ministry of Labour & Employment (Government of India). Annual Report 2022-23 [Internet]. New Delhi, India: Ministry of Labour & Employment. ; 2023. Available from: https://labour.gov.in/sites/default/files/ar_2022_23_english.pdf.

  72. Occupational Knowledge International. Legislative provisions relating to silica exposure and silicosis in India: The need for review [Internet]. Gottesfeld P, editor. 2009. Available from: http://www.okinternational.org/docs/Silica Legislative Review.pdf.

  73. Government of Rajasthan. Rajasthan Policy on Pneumoconiosis including Silicosis Detection, Prevention, Control & Rehabilitation [Internet]. Rajasthan, India: Social Justice and Empowerment Department. ; 2019. Available from: https://sje.rajasthan.gov.in/siteadmin/Uploads/201911211545271328.pdf.

  74. Shafiei M, Ghasemian A, Eslami M, Nojoomi F, Rajabi-Vardanjani H. Risk factors and control strategies for silicotuberculosis as an occupational disease. New Microbes New Infect [Internet]. 2019 [cited 2022 Dec 22];27:75–7. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2052297518301021.

  75. Rees D, Murray J. Silica, silicosis and tuberculosis. Int J Tuberc Lung Dis. 2007;11:474–84.

    CAS  PubMed  Google Scholar 

  76. National Human Rights Commission India. NHRC Interventions on Silicosis [Internet]. Kochher JS, Sarkar UN, editors. New Delhi, India. ; 2016. Available from: https://nhrc.nic.in/sites/default/files/NHRC_Interventions_on_Silicosis_27122016.pdf.

  77. Prajapati SS, Nandi SS, Deshmukh A, Dhatrak SV. Exposure profile of respirable crystalline silica in stone mines in India. J Occup Environ Hyg [Internet]. 2020;17:531–7. Available from: https://doi.org/10.1080/15459624.2020.1798011.

  78. Prajapati SS, Mishra RA, Jhariya B, Dhatrak SV. Respirable dust and crystalline silica exposure among different mining sectors in India. Arch Environ Occup Health [Internet]. 2021;76:455–61. Available from: https://www.tandfonline.com/doi/full/https://doi.org/10.1080/19338244.2021.1919857.

  79. RAMALINGAM MUKHOPADHYAYK, RAMANI A, DASU R, SADASIVAM V, KUMAR A et al. P,. Exposure to Respirable Particulates and Silica in and around the Stone Crushing Units in Central India. Ind Health [Internet]. 2011;49:221–7. Available from: http://www.jstage.jst.go.jp/article/indhealth/49/2/49_MS1207/_article.

  80. MUKHERJEE AK, BHATTACHARYA SK. SAIYED HN. Assessment of Respirable Dust and its Free Silica Contents in Different Indian Coalmines. Ind Health [Internet]. 2005;43:277–84. Available from: http://www.jstage.jst.go.jp/article/indhealth/43/2/43_2_277/_article.

  81. Semple S, Green DA, McAlpine G, Cowie H, Seaton A. Exposure to particulate matter on an Indian stone-crushing site. Occup Environ Med [Internet]. 2008;65:300–5. Available from: https://oem.bmj.com/lookup/doi/https://doi.org/10.1136/oem.2007.032805.

  82. Gottesfeld P, Nicas M, Kephart JW, Balakrishnan K, Rinehart R. Reduction of Respirable Silica Following the Introduction of Water Spray Applications in Indian Stone Crusher Mills. Int J Occup Environ Health [Internet]. 2008;14:94–103. Available from: http://www.tandfonline.com/doi/full/https://doi.org/10.1179/oeh.2008.14.2.94.

  83. Fulekar M. Occupational exposure to dust in quartz manufacturing industry. Ann Occup Hyg [Internet]. 1999;43:269–73. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0003487899000204.

  84. Sivacoumar R, Jayabalou R, Swarnalatha S, Balakrishnan K. Particulate Matter from Stone Crushing Industry: Size Distribution and Health Effects. J Environ Eng [Internet]. 2006;132:405–14. Available from: https://doi.org/10.1061/%28ASCE%290733-9372%282006%29132%3A3%28405%29.

  85. Nandi S, Nimje S, Dhumne U, Dhatrak S. Pulmonary tuberculosis among stone miners of India vis-à-vis silica exposure. Indian J Occup Environ Med [Internet]. 2020;24:102. Available from: http://www.ijoem.com/text.asp?2020/24/2/102/292610.

  86. Bhagia L, Sadhu H. Cost-benefit analysis of installing dust control devices in the agate industry, Khambhat (Gujarat). Indian J Occup Environ Med [Internet]. 2008 [cited 2022 Nov 21];12:128. Available from: http://www.ijoem.com/text.asp?2008/12/3/128/44694.

  87. Meeker JD, Cooper MR, Lefkowitz D, Susi P. Engineering Control Technologies to Reduce Occupational Silica Exposures in Masonry Cutting and Tuckpointing. Public Health Rep [Internet]. 2009 [cited 2022 Dec 14];124:101–11. Available from: http://journals.sagepub.com/doi/https://doi.org/10.1177/00333549091244S112.

  88. Tjoe Nij E, Hilhorst S, Spee T, Spierings J, Steffens F, Lumens M et al. Dust control measures in the construction industry. Ann Occup Hyg [Internet]. 2003 [cited 2022 Dec 14];47:211–8. Available from: https://pubmed.ncbi.nlm.nih.gov/12639834/.

  89. Flynn MR, Susi P. Engineering Controls for Selected Silica and Dust Exposures in the Construction Industry -- A Review. Appl Occup Environ Hyg [Internet]. 2003;18:268–77. Available from: http://www.tandfonline.com/doi/abs/10.1080/10473220301406.

  90. Lahiri S, Levenstein C, Nelson DI, Rosenberg BJ. The cost effectiveness of occupational health interventions: Prevention of silicosis. Am J Ind Med [Internet]. 2005 [cited 2022 Dec 13];48:503–14. Available from: https://onlinelibrary.wiley.com/doi/full/10.1002/ajim.20222.

  91. Rosenberg B, Levenstein C, Spangler E. Change in the world of occupational health: silica control, then and now. J Public Health Policy. 2005;26:192–202.

    Article  PubMed  Google Scholar 

  92. Gottesfeld P, Andrew D, Dalhoff J. Silica exposures in Artisanal Small-Scale Gold Mining in Tanzania and Implications for Tuberculosis Prevention. J Occup Environ Hyg. 2015;12:647–53.

    Article  CAS  PubMed  Google Scholar 

  93. Phillips ML, Johnson AC. Prevalence of dry methods in granite countertop fabrication in Oklahoma. J Occup Environ Hyg. 2012;9:437–42.

    Article  CAS  PubMed  Google Scholar 

  94. Xuan W, Zheng L, Bunes BR, Crane N, Zhou F, Zang L. Engineering solutions to breath tests based on an e-nose system for silicosis screening and early detection in miners. J Breath Res [Internet]. 2022;16:036001. Available from: https://doi.org/10.1088/1752-7163/ac5f13.

  95. Jo B, Khan R. An Internet of Things System for Underground Mine Air Quality Pollutant Prediction Based on Azure Machine Learning. Sensors [Internet]. 2018 [cited 2023 Feb 23];18:930. Available from: https://www.mdpi.com/1424-8220/18/4/930.

  96. Ramdani S, Guettala A, Benmalek M, Aguiar JB. Physical and mechanical performance of concrete made with waste rubber aggregate, glass powder and silica sand powder. J Build Eng [Internet]. 2019;21:302–11. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2352710218307174.

  97. Ghose MK. A perspective on community and state interests in small-scale mining in India including the role of women. Environ Dev Sustain. 2008;10:857–69.

    Article  Google Scholar 

  98. Siriruttanapruk S, Praekunatham H. Integration of basic occupational health services into primary health care in Thailand: Current situation and progress. WHO South-East Asia J Public Heal [Internet]. 2022;11:17. Available from: http://www.who-seajph.org/text.asp?2022/11/1/17/358070.

  99. Madl AK, Donovan EP, Gaffney SH, McKinley MA, Moody EC, Henshaw JL et al. State-of-the-Science Review of the Occupational Health Hazards of Crystalline Silica in Abrasive Blasting Operations and Related Requirements for Respiratory Protection. J Toxicol Environ Heal Part B [Internet]. 2008;11:548–608. Available from: http://www.tandfonline.com/doi/abs/https://doi.org/10.1080/10937400801909135.

  100. Cullinan P, Muñoz X, Suojalehto H, Agius R, Jindal S, Sigsgaard T et al. Occupational lung diseases: from old and novel exposures to effective preventive strategies. Lancet Respir Med [Internet]. 2017;5:445–55. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2213260016304246.

  101. Rahman AP. The Price Of Stone: Children At Risk Of Silicosis In Rajasthan’s Quarries. IndiaSpend [Internet]. 2023 Jan 19 [cited 2023 Jul 2]; Available from: https://www.indiaspend.com/rajasthan/the-price-of-stone-children-at-risk-of-silicosis-in-rajasthans-quarries-849922.

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Acknowledgements

• I would like to express my sincere gratitude to my institute for providing me with the time and resources necessary to write this review article. I am grateful to my colleague, Dr. Sarang Dhatrak, an expert in silicosis, for his valuable inputs. I would like to acknowledge that the views and opinions expressed in this review article are solely personal and do not represent the official stance or viewpoints of my institute or any affiliated organizations. The content of this article is based on independent research and analysis, and any criticism are the author’s own assessment. This disclaimer is intended to clarify that the opinions expressed herein should not be attributed to my institution or its associated entities.

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MR conducted the literature review of relevant studies, arranged the findings under relevant sub-headings of the review, drafted the manuscript, and revised the manuscript. The author synthesized the literature on the topic, with a particular emphasis on identifying key themes (challenges and opportunities) and areas for future research. The author approves the final version of the review.

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Correspondence to Mihir P. Rupani.

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Rupani, M.P. Challenges and opportunities for silicosis prevention and control: need for a national health program on silicosis in India. J Occup Med Toxicol 18, 11 (2023). https://doi.org/10.1186/s12995-023-00379-1

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