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  1. Despite the large amount of experimental studies already conducted on bronchial asthma, further insights into the molecular basics of the disease are required to establish new therapeutic approaches. As a basi...

    Authors: Julia-Annik Börger, Niko Neye, Cristian Scutaru, Carolin Kreiter, Clemens Puk, Tanja C Fischer and Beatrix Groneberg-Kloft
    Citation: Journal of Occupational Medicine and Toxicology 2008 3(Suppl 1):S7
    Content type: Research Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  2. Asthma represents a profound worldwide public health problem. The most effective anti-asthmatic drugs currently available include inhaled β2-agonists and glucocorticoids and control asthma in about 90-95% of p...

    Authors: Gaetano Caramori, David Groneberg, Kazuhiro Ito, Paolo Casolari, Ian M Adcock and Alberto Papi
    Citation: Journal of Occupational Medicine and Toxicology 2008 3(Suppl 1):S6
    Content type: Review Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  3. Toll-like receptors play an important role in innate and adaptive immunity and in balancing immune responses with tolerance. TLR2 is related to protection against allergies and allergic asthma by sensing patho...

    Authors: Barbara Fuchs and Armin Braun
    Citation: Journal of Occupational Medicine and Toxicology 2008 3(Suppl 1):S5
    Content type: Review Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  4. Over the last decade mouse models of experimental asthma proved to be a valuable tool for the investigation of mechanisms that underlie acute allergic airway inflammation and development of airway hyperrespons...

    Authors: Michael Wegmann
    Citation: Journal of Occupational Medicine and Toxicology 2008 3(Suppl 1):S4
    Content type: Review Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  5. Murine models have highlighted the importance of T-cells and TH2 cytokines in development of allergen-induced airway disease. In contrast, the role of mast cells for the development of allergic airway disease has...

    Authors: Sebastian Reuter and Christian Taube
    Citation: Journal of Occupational Medicine and Toxicology 2008 3(Suppl 1):S2
    Content type: Review Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  6. Since 2002, a workshop entitled “Asthma in animal models” has been held once a year in Hannover, Germany. It is organized by the Fraunhofer Institute of Toxicology and Experimental Medicine in collaboration wi...

    Authors: Armin Braun, Thomas Tschernig and David A Groneberg
    Citation: Journal of Occupational Medicine and Toxicology 2008 3(Suppl 1):S1
    Content type: Editorial Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  7. Numerous cross-sectional studies have reported reduced lung function among welders but limitations of exposure assessment and design preclude causal inference. The aim of this study was to investigate if long-...

    Authors: Sigve W Christensen, Jens Peter Bonde and Øyvind Omland
    Citation: Journal of Occupational Medicine and Toxicology 2008 3:6
    Content type: Research Published on:

  8. Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases...

    Authors: Rene Schmidt, Petra Staats, David A Groneberg and Ulrich Wagner
    Citation: Journal of Occupational Medicine and Toxicology 2008 3:5
    Content type: Research Published on:

  9. Significant and poorly documented electrolyte losses result from prolonged sweating. This study aimed to quantify likely sodium losses during work in heat.

    Authors: Graham P Bates and Veronica S Miller
    Citation: Journal of Occupational Medicine and Toxicology 2008 3:4
    Content type: Research Published on:

  10. The objective of the present study is to establish an optimal cutoff point for distress measured with the corresponding scale of the 4DSQ, using the prediction of sickness absence as a criterion. The cutoff po...

    Authors: Willem van Rhenen, Frank JH van Dijk, Wilmar B Schaufeli and Roland WB Blonk
    Citation: Journal of Occupational Medicine and Toxicology 2008 3:3
    Content type: Research Published on:

  11. It was with considerable irony that tribal leaders began a collaboration with the University of Arizona and the Arizona Department of Health Services for training in public health preparedness, as the tribes h...

    Authors: Wayne F Peate and Jennie Mullins
    Citation: Journal of Occupational Medicine and Toxicology 2008 3:2
    Content type: Short report Published on:

  12. In a previous study of computer operators we have demonstrated the relation of upper limb pain to individual and patterns of neurological findings (reduced function of muscles, sensory deviations from normal a...

    Authors: Jorgen R Jepsen and Gert Thomsen
    Citation: Journal of Occupational Medicine and Toxicology 2008 3:1
    Content type: Research Published on:

  13. Exposure to swine barn air is an occupational hazard. Barn workers following an eight-hour work shift develop many signs of lung dysfunction including lung inflammation. However, the in situ cellular and molec...

    Authors: Lakshman Nihal Angunna Gamage, Chandrashekhar Charavaryamath, Trisha Lee Swift and Baljit Singh
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:18
    Content type: Research Published on:

  15. Nanoparticles hold tremendous potential as an effective drug delivery system. In this review we discussed recent developments in nanotechnology for drug delivery. To overcome the problems of gene and drug deli...

    Authors: Sarabjeet Singh Suri, Hicham Fenniri and Baljit Singh
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:16
    Content type: Review Published on:

  17. The textile industry is one of the largest employers in Lithuania. IARC monograph concludes that working in the textile manufacturing industry entails exposures that are possibly carcinogenic to humans. The pu...

    Authors: Irena Kuzmickiene and Mecys Stukonis
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:14
    Content type: Research Published on:

  18. We investigated the association between exposure to trichloroethylene (TCE) and mutations in the von Hippel-Lindau (VHL) gene and the subsequent risk for renal cell carcinoma (RCC).

    Authors: Barbara Charbotel, Sophie Gad, Delphine Caïola, Christophe Béroud, Joelle Fevotte, Alain Bergeret, Sophie Ferlicot and Stéphane Richard
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:13
    Content type: Research Published on:

  19. Occupational physicians are very often confronted with questions as to the fitness of the postural and locomotor systems, especially the spinal column. Occupational medical assessment and advice can be require...

    Authors: Michael Spallek, Walter Kuhn, Sieglinde Schwarze and Bernd Hartmann
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:12
    Content type: Methodology Published on:

  20. Occupational exposures play a role in the onset of several chronic airway diseases. We investigated, in a cross-sectional study, lung function parameters and bronchial hyper-responsiveness to histamine in work...

    Authors: Farid Ould-Kadi, Tim S Nawrot, Peter H Hoet and Benoit Nemery
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:11
    Content type: Research Published on:

  21. The study aimed to i) assess nutritional knowledge in female athletes susceptible to the Female Athlete Triad (FAT) syndrome and to compare with controls; and ii) to compare nutritional knowledge of those who ...

    Authors: Philippa Raymond-Barker, Andrea Petroczi and Eleanor Quested
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:10
    Content type: Research Published on:

  23. The occurrence of occupational lung diseases is decreasing due to improvements in occupational health in recent years; however, silicosis and its complications remain important occupational health problems. We...

    Authors: Iraj Mohebbi, Ebrahim Hassani, Shaker Salarilak and Abdul Rahman Bahrami
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:8
    Content type: Research Published on:

  24. Amongst toxic heavy metals, lead ranks as one of the most serious environmental poisons all over the world. Exposure to lead in the home and the workplace results in health hazards to many adults and children ...

    Authors: D'souza Sunil Herman, Menezes Geraldine and Thuppil Venkatesh
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:7
    Content type: Case report Published on:

  25. Polyvinyl chloride is used in production and manufacturing of many essential tools (e.g. plastic pipes, photography films, etc.). Its production is impossible without the use of vinyl chloride monomer (VCM), w...

    Authors: Mir Saeed Attarchi, Omid Aminian, Mandana Dolati and Maria Mazaheri
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:6
    Content type: Research Published on:

  26. The present study was carried out to determine the effect of cadmium exposure on Urinary N-acetyl-beta -D-glucosaminidase and its isoenzymes A and B in workers exposed at cadmium plating.

    Authors: Ravi Babu Kalahasthi, HR Rajmohan, BK Rajan and Karuna Kumar M
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:5
    Content type: Research Published on:

  28. Many work in injury prone awkward positions that require adequate flexibility and strength in trunk stabilizer muscle groups. Performance on a functional movement screen (FMS) that assessed those factors was c...

    Authors: WF Peate, Gerry Bates, Karen Lunda, Smitha Francis and Kristen Bellamy
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:3
    Content type: Research Published on:

  29. To analyze the relationship between exposure to chlorinated and aromatic organic solvents and malignant lymphoma in a multi-centre, population-based case-control study.

    Authors: Andreas Seidler, Matthias Möhner, Jürgen Berger, Birte Mester, Evelin Deeg, Gine Elsner, Alexandra Nieters and Nikolaus Becker
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:2
    Content type: Research Published on:

  30. Models of isolated and perfused kidneys are used to study the effects of drugs, hazardous or toxic substances on renal functions. Since physiological and morphological parameters of small laboratory animal kid...

    Authors: Volker Unger, Christian Grosse-Siestrup, Claudia Fehrenberg, Axel Fischer, Michael Meissler and David A Groneberg
    Citation: Journal of Occupational Medicine and Toxicology 2007 2:1
    Content type: Research Published on:

  31. Phoenix Firefighters have had abnormally high rates of tuberculin skin test (TBST) results on medical surveillance. The objectives of this study were to evaluate our firefighters using QuantiFERON-TB (QFT), co...

    Authors: James L Fleming, Timothy L England, Howard B Wernick, Steven Reinhart, John A Dominguez, Patrick L Kelley, Forrest D Gorter, Victor Papst and Alicia LaDuke
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:28
    Content type: Research Published on:

  32. Organophosphorus (OPs) pesticides are the most commonly used pesticides in Peruvian agriculture. The population at risk for OPs exposure includes formulators, applicators and farmers. Majes Valley is the most ...

    Authors: Sandra Yucra, Kyle Steenland, Arturo Chung, Fredy Choque and Gustavo F Gonzales
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:27
    Content type: Research Published on:

  34. Shift work exerts major influences on the physiological functions of the human body. These are primarily mediated by the disruption of circadian rhythms since most body functions are circadian rhythmic. Next t...

    Authors: Anke van Mark, Michael Spallek, Richard Kessel and Elke Brinkmann
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:25
    Content type: Review Published on:

  35. This study examined the association between psychosocial and organizational work conditions and mental health among women employed in the cleaning profession in Norway.

    Authors: Migle Gamperiene, Jan F Nygård, Inger Sandanger, Morten Wærsted and Dag Bruusgaard
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:24
    Content type: Research Published on:

  37. Cadmium (Cd) has been in industrial use for a long period of time. Its serious toxicity moved into scientific focus during the middle of the last century. In this review, we discuss historic and recent develop...

    Authors: Johannes Godt, Franziska Scheidig, Christian Grosse-Siestrup, Vera Esche, Paul Brandenburg, Andrea Reich and David A Groneberg
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:22
    Content type: Review Published on:

  39. This research work is dedicated to occupational health problems caused by ergonomic risks. The research object was road building industry, where workers have to work very intensively, have long work hours, are...

    Authors: Zenija Roja, Valdis Kalkis, Arved Vain, Henrijs Kalkis and Maija Eglite
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:20
    Content type: Research Published on:

  42. There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or an...

    Authors: Gintautas Korinth, Tobias Weiss, Jürgen Angerer and Hans Drexler
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:17
    Content type: Case report Published on:

  43. A case of cyclobenzaprine (flexeril) overdose and the resultant rhabdomyolysis is presented. A review of the range of clinical toxicity, management of overdose is described. The similarity of cyclobenzaprine t...

    Authors: Shiven B Chabria
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:16
    Content type: Case report Published on:

  44. Our study was aimed to investigate in a German collective if there are any hints for an increased occupational or environmental risk to develop systemic sclerosis, especially, focussing on work-related exposur...

    Authors: Birgitta Kütting, Wolfgang Uter and Hans Drexler
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:15
    Content type: Research Published on:

  45. Chronic neck pain is widely prevalent and a common source of disability in the working-age population. Etiology of chronic neck pain includes neck sprain, mechanical or muscular neck pain, myofascial pain synd...

    Authors: Gertrud Kirchhoff, Chlodwig Kirchhoff, Sonja Buhmann, Karl-Georg Kanz, Miriam Lenz, Tobias Vogel and Rainer Maria Kichhoff
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:14
    Content type: Case report Published on:

  46. Occupational exposure to airborne low molecular weight chemicals, like trimellitic anhydride (TMA), can result in occupational asthma. Alveolar macrophages (AMs) are among the first cells to encounter these in...

    Authors: Dingena L Valstar, Marcel A Schijf, Erietta Stelekati, Frans P Nijkamp, Nanne Bloksma and Paul AJ Henricks
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:13
    Content type: Research Published on:

  47. Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far. To iden...

    Authors: Ulrich Wagner, Petra Staats, Hans-Christoph Fehmann, Axel Fischer, Tobias Welte and David A Groneberg
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:12
    Content type: Research Published on:

  49. Swine production has undergone rapid transformation from family owned operation to a large scale industrial enterprise. Since increasing number of pigs are reared on a large scale in confined buildings, some o...

    Authors: Chandrashekhar Charavaryamath and Baljit Singh
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:10
    Content type: Review Published on:

  50. 4,4'-Diaminodiphenylsulphone (Dapsone) is widely used for a variety of infectious, immune and hypersensitivity disorders, with indications ranging from Hansen's disease, inflammatory disease and insect bites, ...

    Authors: Semaan G Kosseifi, Bhuvana Guha, Dima N Nassour, David S Chi and Guha Krishnaswamy
    Citation: Journal of Occupational Medicine and Toxicology 2006 1:9
    Content type: Case report Published on:
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  • ISSN: 1745-6673 (electronic)

Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673